Anoshchenko O - Search Results

1

Pharmacokinetics, Mass Balance, Safety, and Tolerability of Obeldesivir in Healthy Participants.

Anoshchenko O, Abdelghany M, Lichtman A, Duan R, Chen H, Shaik NA, Peng CC, Yue Q, Subramanian R, Hyland RH, Davies S, Castellanos K, Mak L, Shen G, Xiao D, Caro L, Winter H, Llewellyn J, Humeniuk R. Anoshchenko O, et al. Clin Pharmacol Ther. 2024 Nov;116(5):1231-1239. doi: 10.1002/cpt.3337. Epub 2024 Jun 28. Clin Pharmacol Ther. 2024. PMID: 38940465 Clinical Trial.

2

Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants.

Humeniuk R, Juneja K, Chen S, Ellis S, Anoshchenko O, Xiao D, Share A, Johnston M, Davies S, DeZure A, Llewellyn J, Osinusi A, Winter H, Girish S, Palaparthy R, Dresser M. Humeniuk R, et al. Among authors: anoshchenko o. Clin Transl Sci. 2023 Nov;16(11):2276-2288. doi: 10.1111/cts.13627. Epub 2023 Sep 25. Clin Transl Sci. 2023. PMID: 37688349 Free PMC article. Clinical Trial.

3

Resistance Analyses in Highly Treatment-Experienced People With Human Immunodeficiency Virus (HIV) Treated With the Novel Capsid HIV Inhibitor Lenacapavir.

Margot NA, Naik V, VanderVeen L, Anoshchenko O, Singh R, Dvory-Sobol H, Rhee MS, Callebaut C. Margot NA, et al. Among authors: anoshchenko o. J Infect Dis. 2022 Nov 28;226(11):1985-1991. doi: 10.1093/infdis/jiac364. J Infect Dis. 2022. PMID: 36082606

4

Characterizing and Quantifying Extrahepatic Metabolism of (-)-Δ⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, (±)-11-Hydroxy-Δ⁹-THC (11-OH-THC).

Kumar AR, Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Kumar AR, et al. Among authors: anoshchenko o. Drug Metab Dispos. 2022 Jun;50(6):734-740. doi: 10.1124/dmd.122.000868. Epub 2022 Apr 3. Drug Metab Dispos. 2022. PMID: 35370140 Free PMC article.

5

Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation.

Anoshchenko O, Storelli F, Unadkat JD. Anoshchenko O, et al. Drug Metab Dispos. 2021 Oct;49(10):919-928. doi: 10.1124/dmd.121.000538. Epub 2021 Aug 23. Drug Metab Dispos. 2021. PMID: 34426410 Free PMC article.

6

Estimating fetal exposure to the P-gp substrates, corticosteroids, by PBPK modeling to inform prevention of neonatal respiratory distress syndrome.

Anoshchenko O, Milad MA, Unadkat JD. Anoshchenko O, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):1057-1070. doi: 10.1002/psp4.12674. Epub 2021 Jul 23. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34273255 Free PMC article.

7

Novel Trifluoromethyl Pyrimidinone Compounds With Activity Against Mycobacterium tuberculosis.

Hembre E, Early JV, Odingo J, Shelton C, Anoshchenko O, Guzman J, Flint L, Dennison D, McNeil MB, Korkegian A, Ovechkina Y, Ornstein P, Masquelin T, Hipskind PA, Parish T. Hembre E, et al. Among authors: anoshchenko o. Front Chem. 2021 Apr 29;9:613349. doi: 10.3389/fchem.2021.613349. eCollection 2021. Front Chem. 2021. PMID: 33996738 Free PMC article.

8

Successful Prediction of Human Steady-State Unbound Brain-to-Plasma Concentration Ratio of P-gp Substrates Using the Proteomics-Informed Relative Expression Factor Approach.

Storelli F, Anoshchenko O, Unadkat JD. Storelli F, et al. Among authors: anoshchenko o. Clin Pharmacol Ther. 2021 Aug;110(2):432-442. doi: 10.1002/cpt.2227. Epub 2021 May 1. Clin Pharmacol Ther. 2021. PMID: 33675056 Free PMC article.

9

Gestational Age-Dependent Abundance of Human Placental Transporters as Determined by Quantitative Targeted Proteomics.

Anoshchenko O, Prasad B, Neradugomma NK, Wang J, Mao Q, Unadkat JD. Anoshchenko O, et al. Drug Metab Dispos. 2020 Sep;48(9):735-741. doi: 10.1124/dmd.120.000067. Epub 2020 Jun 26. Drug Metab Dispos. 2020. PMID: 32591415 Free PMC article.

10

Hepatic Enzymes Relevant to the Disposition of (-)-∆⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC.

Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Patilea-Vrana GI, et al. Among authors: anoshchenko o. Drug Metab Dispos. 2019 Mar;47(3):249-256. doi: 10.1124/dmd.118.085548. Epub 2018 Dec 19. Drug Metab Dispos. 2019. PMID: 30567877 Free PMC article.

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