Seubert JM - Search Results

1

Linoleic acid-derived diol 12,13-DiHOME enhances NLRP3 inflammasome activation in macrophages.

Valencia R, Kranrod JW, Fang L, Soliman AM, Azer B, Clemente-Casares X, Seubert JM. Valencia R, et al. Among authors: seubert jm. FASEB J. 2024 Jul 15;38(13):e23748. doi: 10.1096/fj.202301640RR. FASEB J. 2024. PMID: 38940767

2

Cardioprotective effects of CYP-derived epoxy metabolites of docosahexaenoic acid involve limiting NLRP3 inflammasome activation ¹.

Darwesh AM, Jamieson KL, Wang C, Samokhvalov V, Seubert JM. Darwesh AM, et al. Among authors: seubert jm. Can J Physiol Pharmacol. 2019 Jun;97(6):544-556. doi: 10.1139/cjpp-2018-0480. Epub 2018 Oct 16. Can J Physiol Pharmacol. 2019. PMID: 30326194

3

Genetic Deletion or Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Cardiac Ischemia/Reperfusion Injury by Attenuating NLRP3 Inflammasome Activation.

Darwesh AM, Keshavarz-Bahaghighat H, Jamieson KL, Seubert JM. Darwesh AM, et al. Among authors: seubert jm. Int J Mol Sci. 2019 Jul 17;20(14):3502. doi: 10.3390/ijms20143502. Int J Mol Sci. 2019. PMID: 31319469 Free PMC article.

4

Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure.

Byrne NJ, Matsumura N, Maayah ZH, Ferdaoussi M, Takahara S, Darwesh AM, Levasseur JL, Jahng JWS, Vos D, Parajuli N, El-Kadi AOS, Braam B, Young ME, Verma S, Light PE, Sweeney G, Seubert JM, Dyck JRB. Byrne NJ, et al. Among authors: seubert jm. Circ Heart Fail. 2020 Jan;13(1):e006277. doi: 10.1161/CIRCHEARTFAILURE.119.006277. Epub 2020 Jan 20. Circ Heart Fail. 2020. PMID: 31957470

5

Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure.

Byrne NJ, Soni S, Takahara S, Ferdaoussi M, Al Batran R, Darwesh AM, Levasseur JL, Beker D, Vos DY, Schmidt MA, Alam AS, Maayah ZH, Schertzer JD, Seubert JM, Ussher JR, Dyck JRB. Byrne NJ, et al. Among authors: seubert jm. Circ Heart Fail. 2020 Jun;13(6):e006573. doi: 10.1161/CIRCHEARTFAILURE.119.006573. Epub 2020 Jun 4. Circ Heart Fail. 2020. PMID: 32493060

6

A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3-NLRP3 Pathway.

Darwesh AM, Bassiouni W, Adebesin AM, Mohammad AS, Falck JR, Seubert JM. Darwesh AM, et al. Among authors: seubert jm. Int J Mol Sci. 2020 Jul 24;21(15):5261. doi: 10.3390/ijms21155261. Int J Mol Sci. 2020. PMID: 32722183 Free PMC article.

7

Changes in the Left Ventricular Eicosanoid Profile in Human Dilated Cardiomyopathy.

Sosnowski DK, Jamieson KL, Darwesh AM, Zhang H, Keshavarz-Bahaghighat H, Valencia R, Viveiros A, Edin ML, Zeldin DC, Oudit GY, Seubert JM. Sosnowski DK, et al. Among authors: seubert jm. Front Cardiovasc Med. 2022 May 19;9:879209. doi: 10.3389/fcvm.2022.879209. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35665247 Free PMC article.

8

PINK1-dependent and Parkin-independent mitophagy is involved in reprogramming of glycometabolism in pancreatic cancer cells.

Miyazaki N, Shiratori R, Oshima T, Zhang Z, Valencia R, Kranrod J, Fang L, Seubert JM, Ito K, Aoki S. Miyazaki N, et al. Among authors: seubert jm. Biochem Biophys Res Commun. 2022 Oct 15;625:167-173. doi: 10.1016/j.bbrc.2022.08.004. Epub 2022 Aug 5. Biochem Biophys Res Commun. 2022. PMID: 35963163

9

Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function.

Sosnowski DK, Jamieson KL, Gruzdev A, Li Y, Valencia R, Yousef A, Kassiri Z, Zeldin DC, Seubert JM. Sosnowski DK, et al. Among authors: seubert jm. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H670-H687. doi: 10.1152/ajpheart.00217.2022. Epub 2022 Aug 19. Am J Physiol Heart Circ Physiol. 2022. PMID: 35985007 Free PMC article.

10

Cardiomyocyte-specific CYP2J2 and its therapeutic implications.

Valencia R, Bassiouni W, Darwesh AM, Bapuji R, Seubert JM. Valencia R, et al. Among authors: seubert jm. Expert Opin Drug Metab Toxicol. 2022 Jul-Aug;18(7-8):423-439. doi: 10.1080/17425255.2022.2114344. Epub 2022 Sep 9. Expert Opin Drug Metab Toxicol. 2022. PMID: 35997132 Review.

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