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IRF4 impedes human CD8 T cell function and promotes cell proliferation and PD-1 expression.
Hirsch T, Neyens D, Duhamel C, Bayard A, Vanhaver C, Luyckx M, Sala de Oyanguren F, Wildmann C, Dauguet N, Squifflet JL, Montiel V, Deschamps M, van der Bruggen P. Hirsch T, et al. Among authors: van der bruggen p. Cell Rep. 2024 Jul 23;43(7):114401. doi: 10.1016/j.celrep.2024.114401. Epub 2024 Jun 27. Cell Rep. 2024. PMID: 38943641 Free article.
HELIOS-expressing human CD8 T cells exhibit limited effector functions.
Neyens D, Hirsch T, Abdel Aziz Issa Abdel Hadi A, Dauguet N, Vanhaver C, Bayard A, Wildmann C, Luyckx M, Squifflet JL, D'Hondt Q, Duhamel C, Huaux A, Montiel V, Dechamps M, van der Bruggen P. Neyens D, et al. Among authors: van der bruggen p. Front Immunol. 2023 Dec 22;14:1308539. doi: 10.3389/fimmu.2023.1308539. eCollection 2023. Front Immunol. 2023. PMID: 38187391 Free PMC article.
Identification of an Immature Subset of PMN-MDSC Correlated to Response to Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma.
Gondois-Rey F, Paul M, Alcaraz F, Bourass S, Monnier J, Malissen N, Grob JJ, Bruger AM, Van Der Bruggen P, Gaudy-Marqueste C, Olive D. Gondois-Rey F, et al. Among authors: van der bruggen p. Cancers (Basel). 2021 Mar 17;13(6):1362. doi: 10.3390/cancers13061362. Cancers (Basel). 2021. PMID: 33802925 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Among authors: van der bruggen p. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166.
Renard HF, Tyckaert F, Lo Giudice C, Hirsch T, Valades-Cruz CA, Lemaigre C, Shafaq-Zadah M, Wunder C, Wattiez R, Johannes L, van der Bruggen P, Alsteens D, Morsomme P. Renard HF, et al. Among authors: van der bruggen p. Nat Commun. 2020 Mar 19;11(1):1457. doi: 10.1038/s41467-020-15303-y. Nat Commun. 2020. PMID: 32193381 Free PMC article.
Protocol to assess the suppression of T-cell proliferation by human MDSC.
Bruger AM, Vanhaver C, Bruderek K, Amodio G, Tavukçuoğlu E, Esendagli G, Gregori S, Brandau S, van der Bruggen P. Bruger AM, et al. Among authors: van der bruggen p. Methods Enzymol. 2020;632:155-192. doi: 10.1016/bs.mie.2019.05.046. Epub 2019 Jul 8. Methods Enzymol. 2020. PMID: 32000895
141 results