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Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumors.
Mu C, Liu X, Riselli A, Slater J, Escobar E, Dang D, Drapeau S, Delos Santos R, Andosca S, Nguyen H, Larson PEZ, Bok R, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. Mu C, et al. STAR Protoc. 2024 Sep 20;5(3):103091. doi: 10.1016/j.xpro.2024.103091. Epub 2024 Jun 28. STAR Protoc. 2024. PMID: 38943645 Free PMC article.
Here, we present a protocol for preparing a hyperpolarized (HP) (13)C-bicarbonate tissue pH MRI imaging contrast agent to detect aggressive tumors. We describe the steps for the formulation and polarization of a precursor molecule (13)C-glycerol carbonate ((13)C
Here, we present a protocol for preparing a hyperpolarized (HP) (13)C-bicarbonate tissue pH MRI imaging contrast agent to detect aggr …
Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13 C,15 N2 ]urea + [1-13 C]pyruvate simultaneous perfusion and metabolic imaging.
Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ. Liu X, et al. Among authors: mu c. Magn Reson Med. 2022 Sep;88(3):1039-1054. doi: 10.1002/mrm.29266. Epub 2022 May 8. Magn Reson Med. 2022. PMID: 35526263 Free PMC article.
Prostate-Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate Cancer.
Meher N, Ashley GW, Bobba KN, Wadhwa A, Bidkar AP, Dasari C, Mu C, Sankaranarayanan RA, Serrano JAC, Raveendran A, Bulkley DP, Aggarwal R, Greenland NY, Oskowitz A, Wilson DM, Seo Y, Santi DV, VanBrocklin HF, Flavell RR. Meher N, et al. Among authors: mu c. Adv Healthc Mater. 2024 Jul;13(19):e2304618. doi: 10.1002/adhm.202304618. Epub 2024 May 17. Adv Healthc Mater. 2024. PMID: 38700450
PET Imaging Using 89Zr Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention (EPR) in Prostate Cancer.
Meher N, Bidkar AP, Wadhwa A, Bobba KN, Dhrona S, Dasari C, Mu C, Fong COY, Cámara JA, Ali U, Basak M, Bulkley D, Steri V, Fontaine SD, Zhu J, Oskowitz A, Aggarwal RR, Sriram R, Chou J, Wilson DM, Seo Y, Santi DV, Ashley GW, VanBrocklin HF, Flavell RR. Meher N, et al. Among authors: mu c. Mol Cancer Ther. 2024 Sep 27. doi: 10.1158/1535-7163.MCT-24-0024. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39331510
1,009 results