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Page 1
Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Gerhart JG, Carreño FO, Edginton AN, Sinha J, Perrin EM, Kumar KR, Rikhi A, Hornik CP, Harris V, Ganguly S, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: carreno fo. Clin Pharmacokinet. 2022 Feb;61(2):307-320. doi: 10.1007/s40262-021-01072-4. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617262 Free PMC article.
Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity.
Gerhart JG, Carreño FO, Loop MS, Lee CR, Edginton AN, Sinha J, Kumar KR, Kirkpatrick CM, Hornik CP, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: carreno fo. Clin Pharmacol Ther. 2022 Aug;112(2):391-403. doi: 10.1002/cpt.2618. Epub 2022 May 18. Clin Pharmacol Ther. 2022. PMID: 35451072 Free PMC article.
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Gerhart JG, Carreño FO, Ford JL, Edginton AN, Perrin EM, Watt KM, Muller WJ, Atz AM, Al-Uzri A, Delmore P, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: carreno fo. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):778-791. doi: 10.1002/psp4.12793. Epub 2022 May 2. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35491971 Free PMC article.
Quantification of neurotransmitters in microdialysate samples following quetiapine dosing to schizophrenia phenotyped rats using a validated LC-MS/MS method.
Carreño F, Helfer VE, Staudt KJ, Olivo LB, Barreto F, Herrmann AP, Rates SMK, Dalla Costa T. Carreño F, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Oct 15;1155:122282. doi: 10.1016/j.jchromb.2020.122282. Epub 2020 Jul 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 32771966
Semi-Mechanistic Pharmacokinetic Modeling of Lipid Core Nanocapsules: Understanding Quetiapine Plasma and Brain Disposition in a Neurodevelopmental Animal Model of Schizophrenia.
Carreño F, Helfer VE, Staudt KJ, Olivo LB, Paese K, Meyer FS, Herrmann AP, Guterres SS, Kuze Rates SM, Trocóniz I, Dalla Costa T. Carreño F, et al. J Pharmacol Exp Ther. 2020 Oct;375(1):49-58. doi: 10.1124/jpet.120.000109. Epub 2020 Jul 27. J Pharmacol Exp Ther. 2020. PMID: 32719070
Pharmacokinetic/pharmacodynamic modeling of cortical dopamine concentrations after quetiapine lipid core nanocapsules administration to schizophrenia phenotyped rats.
Dias BB, Carreño F, Helfer VE, Olivo LB, Staudt KJ, Paese K, Barreto F, Meyer FS, Herrmann AP, Guterres SS, Rates SMK, de Araújo BV, Trocóniz IF, Dalla Costa T. Dias BB, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Apr;13(4):638-648. doi: 10.1002/psp4.13107. Epub 2024 Jan 28. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38282365 Free PMC article.
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