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X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction.
Zhang P, Munier JJ, Wiese CB, Vergnes L, Link JC, Abbasi F, Ronquillo E, Scheker K, Muñoz A, Kuang YL, Theusch E, Lu M, Sanchez G, Oni-Orisan A, Iribarren C, McPhaul MJ, Nomura DK, Knowles JW, Krauss RM, Medina MW, Reue K. Zhang P, et al. Among authors: nomura dk. Nat Commun. 2024 Jul 2;15(1):5571. doi: 10.1038/s41467-024-49764-2. Nat Commun. 2024. PMID: 38956041 Free PMC article.
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR. Lee J, et al. Among authors: nomura dk. Nature. 2019 Apr;568(7751):254-258. doi: 10.1038/s41586-019-1005-x. Epub 2019 Mar 6. Nature. 2019. PMID: 30842661 Free PMC article.
Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.
Lin H, Long JZ, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM. Lin H, et al. Among authors: nomura dk. J Med Chem. 2018 Apr 12;61(7):3224-3230. doi: 10.1021/acs.jmedchem.8b00029. Epub 2018 Mar 22. J Med Chem. 2018. PMID: 29533650 Free PMC article.
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Bersuker K, et al. Among authors: nomura dk. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. Nature. 2019. PMID: 31634900 Free PMC article.
182 results