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Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial.
Farr JN, Atkinson EJ, Achenbach SJ, Volkman TL, Tweed AJ, Vos SJ, Ruan M, Sfeir J, Drake MT, Saul D, Doolittle ML, Bancos I, Yu K, Tchkonia T, LeBrasseur NK, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: ruan m. Nat Med. 2024 Sep;30(9):2605-2612. doi: 10.1038/s41591-024-03096-2. Epub 2024 Jul 2. Nat Med. 2024. PMID: 38956196 Clinical Trial.
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair.
Saul D, Doolittle ML, Rowsey JL, Froemming MN, Kosinsky RL, Vos SJ, Ruan M, LeBrasseur N, Chandra A, Pignolo R, Passos JF, Farr JN, Monroe DG, Khosla S. Saul D, et al. Among authors: ruan m. bioRxiv [Preprint]. 2024 Feb 7:2024.02.01.578420. doi: 10.1101/2024.02.01.578420. bioRxiv. 2024. Update in: J Clin Invest. 2024 May 16;134(12):e179834. doi: 10.1172/JCI179834 PMID: 38370844 Free PMC article. Updated. Preprint.
718 results