Werner B - Search Results

1

Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer.

Kayhanian H, Cross W, van der Horst SEM, Barmpoutis P, Lakatos E, Caravagna G, Zapata L, Van Hoeck A, Middelkamp S, Litchfield K, Steele C, Waddingham W, Patel D, Milite S, Jin C, Baker AM, Alexander DC, Khan K, Hochhauser D, Novelli M, Werner B, van Boxtel R, Hageman JH, Buissant des Amorie JR, Linares J, Ligtenberg MJL, Nagtegaal ID, Laclé MM, Moons LMG, Brosens LAA, Pillay N, Sottoriva A, Graham TA, Rodriguez-Justo M, Shiu KK, Snippert HJG, Jansen M. Kayhanian H, et al. Among authors: werner b. Nat Genet. 2024 Jul;56(7):1420-1433. doi: 10.1038/s41588-024-01777-9. Epub 2024 Jul 3. Nat Genet. 2024. PMID: 38956208 Free PMC article.

2

Identification of neutral tumor evolution across cancer types.

Williams MJ, Werner B, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: werner b. Nat Genet. 2016 Mar;48(3):238-244. doi: 10.1038/ng.3489. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780609 Free PMC article.

3

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

Werner B, Scott JG, Sottoriva A, Anderson AR, Traulsen A, Altrock PM. Werner B, et al. Cancer Res. 2016 Apr 1;76(7):1705-13. doi: 10.1158/0008-5472.CAN-15-2069. Epub 2016 Feb 1. Cancer Res. 2016. PMID: 26833122 Free PMC article.

4

Functional versus non-functional intratumor heterogeneity in cancer.

Williams MJ, Werner B, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: werner b. Mol Cell Oncol. 2016 Apr 22;3(4):e1162897. doi: 10.1080/23723556.2016.1162897. eCollection 2016 Jul. Mol Cell Oncol. 2016. PMID: 27652316 Free PMC article.

5

Detecting truly clonal alterations from multi-region profiling of tumours.

Werner B, Traulsen A, Sottoriva A, Dingli D. Werner B, et al. Sci Rep. 2017 Mar 27;7:44991. doi: 10.1038/srep44991. Sci Rep. 2017. PMID: 28344344 Free PMC article.

6

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures.

Williams MJ, Werner B, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: werner b. Nat Genet. 2017 Aug 30;49(9):1289-1291. doi: 10.1038/ng.3877. Nat Genet. 2017. PMID: 28854180 No abstract available.

7

Quantification of subclonal selection in cancer from bulk sequencing data.

Williams MJ, Werner B, Heide T, Curtis C, Barnes CP, Sottoriva A, Graham TA. Williams MJ, et al. Among authors: werner b. Nat Genet. 2018 Jun;50(6):895-903. doi: 10.1038/s41588-018-0128-6. Epub 2018 May 28. Nat Genet. 2018. PMID: 29808029 Free PMC article.

8

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates.

Werner B, Sottoriva A. Werner B, et al. PLoS Comput Biol. 2018 Jun 7;14(6):e1006233. doi: 10.1371/journal.pcbi.1006233. eCollection 2018 Jun. PLoS Comput Biol. 2018. PMID: 29879111 Free PMC article.

9

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data.

Williams MJ, Werner B, Heide T, Curtis C, Barnes CP, Sottoriva A, Graham TA. Williams MJ, et al. Among authors: werner b. Nat Genet. 2018 Sep;50(9):1342. doi: 10.1038/s41588-018-0169-x. Nat Genet. 2018. PMID: 30022114

10

Reply to 'Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data'.

Williams MJ, Werner B, Heide T, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: werner b. Nat Genet. 2018 Dec;50(12):1628-1630. doi: 10.1038/s41588-018-0210-0. Nat Genet. 2018. PMID: 30250125 No abstract available.

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