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From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation.
Soni D, Borriello F, Scott DA, Feru F, DeLeon M, Brightman SE, Cheng WK, Melhem G, Smith JA, Ramirez JC, Barman S, Cameron M, Kelly A, Walker K, Nanishi E, van Haren SD, Phan T, Qi Y, Kinsey R, Raczy MM, Ozonoff A, Pettengill MA, Hubbell JA, Fox CB, Dowling DJ, Levy O. Soni D, et al. Among authors: fox cb. Sci Adv. 2024 Jul 5;10(27):eadg3747. doi: 10.1126/sciadv.adg3747. Epub 2024 Jul 3. Sci Adv. 2024. PMID: 38959314 Free PMC article.
Development of thermostable vaccine adjuvants.
Qi Y, Fox CB. Qi Y, et al. Among authors: fox cb. Expert Rev Vaccines. 2021 May;20(5):497-517. doi: 10.1080/14760584.2021.1902314. Epub 2021 Jun 26. Expert Rev Vaccines. 2021. PMID: 33724133 Free PMC article. Review.
Formulated Phospholipids as Non-Canonical TLR4 Agonists.
Liang H, Lykins WR, Seydoux E, Guderian JA, Phan T, Fox CB, Orr MT. Liang H, et al. Among authors: fox cb. Pharmaceutics. 2022 Nov 22;14(12):2557. doi: 10.3390/pharmaceutics14122557. Pharmaceutics. 2022. PMID: 36559051 Free PMC article.
Semi-synthetic terpenoids with differential adjuvant properties as sustainable replacements for shark squalene in vaccine emulsions.
Fisher KJ, Kinsey R, Mohamath R, Phan T, Liang H, Orr MT, Lykins WR, Guderian JA, Bakken J, Argilla D, Ramer-Denisoff G, Larson E, Qi Y, Sivananthan S, Smolyar K, Carter D, Paddon CJ, Fox CB. Fisher KJ, et al. Among authors: fox cb. NPJ Vaccines. 2023 Feb 16;8(1):14. doi: 10.1038/s41541-023-00608-y. NPJ Vaccines. 2023. PMID: 36797262 Free PMC article.
Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques.
Abhyankar MM, Xu F, Chavez D, Goodroe A, Mendoza E, Chen C, Singh DK, Varnador F Jr, Sivananthan SJ, Kinsey R, Lykins WR, Murphy BM, Martin AR, Tomai MA, Ghosal S, Casper C, Pedersen K, Petri WA Jr, Fox CB. Abhyankar MM, et al. Among authors: fox cb. Hum Vaccin Immunother. 2024 Dec 31;20(1):2374147. doi: 10.1080/21645515.2024.2374147. Epub 2024 Aug 1. Hum Vaccin Immunother. 2024. PMID: 39090779 Free PMC article.
161 results