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Page 1
MCT1-dependent lactate recycling is a metabolic vulnerability in colorectal cancer cells upon acquired resistance to anti-EGFR targeted therapy.
Richiardone E, Al Roumi R, Lardinois F, Giolito MV, Ambroise J, Boidot R, Drotleff B, Ghesquière B, Bellahcène A, Bardelli A, Arena S, Corbet C. Richiardone E, et al. Among authors: ghesquiere b. Cancer Lett. 2024 Aug 28;598:217091. doi: 10.1016/j.canlet.2024.217091. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964730 Free article.
13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation and exhaustion.
Kirchmair A, Nemati N, Lamberti G, Trefny M, Krogsdam A, Siller A, Hörtnagl P, Schumacher P, Sopper S, Sandbichler A, Zippelius A, Ghesquière B, Trajanoski Z. Kirchmair A, et al. Among authors: ghesquiere b. Front Immunol. 2023 Oct 19;14:1267816. doi: 10.3389/fimmu.2023.1267816. eCollection 2023. Front Immunol. 2023. PMID: 37928527 Free PMC article.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Sneyers F, Kerkhofs M, Speelman-Rooms F, Welkenhuyzen K, La Rovere R, Shemy A, Voet A, Eelen G, Dewerchin M, Tait SWG, Ghesquière B, Bootman MD, Bultynck G. Sneyers F, et al. Among authors: ghesquiere b. Cell Death Dis. 2023 Sep 8;14(9):600. doi: 10.1038/s41419-023-06120-4. Cell Death Dis. 2023. PMID: 37684238 Free PMC article.
Endothelial metabolic control of insulin sensitivity through resident macrophages.
Zhang J, Sjøberg KA, Gong S, Wang T, Li F, Kuo A, Durot S, Majcher A, Ardicoglu R, Desgeorges T, Mann CG, Soro Arnáiz I, Fitzgerald G, Gilardoni P, Abel ED, Kon S, Olivares-Villagómez D, Zamboni N, Wolfrum C, Hornemann T, Morscher R, Tisch N, Ghesquière B, Kopf M, Richter EA, De Bock K. Zhang J, et al. Among authors: ghesquiere b. Cell Metab. 2024 Nov 5;36(11):2383-2401.e9. doi: 10.1016/j.cmet.2024.08.008. Epub 2024 Sep 12. Cell Metab. 2024. PMID: 39270655 Free article.
Glucocorticoid dysfunction in children with severe malaria.
Vandermosten L, Prenen F, Fogang B, Dagneau de Richecour P, Knoops S, Donkeu CJ, Nguefack CDP, Taguebue JV, Ndombo PK, Ghesquière B, Ayong L, Van den Steen PE. Vandermosten L, et al. Among authors: ghesquiere b. Front Immunol. 2023 Jul 10;14:1187196. doi: 10.3389/fimmu.2023.1187196. eCollection 2023. Front Immunol. 2023. PMID: 37492570 Free PMC article.
Glycosphingolipids in congenital disorders of glycosylation (CDG).
Jáñez Pedrayes A, Rymen D, Ghesquière B, Witters P. Jáñez Pedrayes A, et al. Among authors: ghesquiere b. Mol Genet Metab. 2024 May;142(1):108434. doi: 10.1016/j.ymgme.2024.108434. Epub 2024 Mar 5. Mol Genet Metab. 2024. PMID: 38489976 Review.
141 results