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Impaired 11β-hydroxysteroid dehydrogenase type 2 activity in kidney disease disrupts 11-oxygenated androgen biosynthesis.
Tomkins M, McDonnell T, Cussen L, Sagmeister MS, Oestlund I, Shaheen F, Harper L, Hardy RS, Taylor AE, Gilligan LC, Arlt W, McIlroy M, de Freitas D, Conlon P, Magee C, Denton M, O'Seaghdha C, Snoep JL, Storbeck KH, Sherlock M, O'Reilly MW. Tomkins M, et al. Among authors: hardy rs. J Clin Endocrinol Metab. 2024 Oct 9:dgae714. doi: 10.1210/clinem/dgae714. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39382395
Glucocorticoid excess alters metabolic rate and substrate utilisation via 11β-HSD1.
Heaselgrave SR, Heising S, Morgan SA, Carthwright DM, Sagmeister M, Hardy RS, Doig CL, Morton N, Tsintzas K, Lavery GG. Heaselgrave SR, et al. Among authors: hardy rs. J Endocrinol. 2024 Oct 28;263(2):e240205. doi: 10.1530/JOE-24-0205. Print 2024 Nov 1. J Endocrinol. 2024. PMID: 39302000 Free PMC article.
1,569 results