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Hippo pathway effector YAP inhibition restores the sensitivity of EGFR-TKI in lung adenocarcinoma having primary or acquired EGFR-TKI resistance.
Lee JE, Park HS, Lee D, Yoo G, Kim T, Jeon H, Yeo MK, Lee CS, Moon JY, Jung SS, Kim JO, Kim SY, Park DI, Park YH, Lee JC, Oh IJ, Lim DS, Chung C. Lee JE, et al. Among authors: kim t, kim jo, kim sy. Biochem Biophys Res Commun. 2016 May 20;474(1):154-160. doi: 10.1016/j.bbrc.2016.04.089. Epub 2016 Apr 20. Biochem Biophys Res Commun. 2016. PMID: 27105908
The E3 ubiquitin ligase CHIP selectively regulates mutant epidermal growth factor receptor by ubiquitination and degradation.
Chung C, Yoo G, Kim T, Lee D, Lee CS, Cha HR, Park YH, Moon JY, Jung SS, Kim JO, Lee JC, Kim SY, Park HS, Park M, Park DI, Lim DS, Jang KW, Lee JE. Chung C, et al. Among authors: kim t, kim jo, kim sy. Biochem Biophys Res Commun. 2016 Oct 14;479(2):152-158. doi: 10.1016/j.bbrc.2016.07.111. Epub 2016 Jul 28. Biochem Biophys Res Commun. 2016. PMID: 27475501
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