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Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis.
Grimsrud MM, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, Braadland PR, Charbel A, Metzger C, Albrecht T, Steiert TA, Schlesner M, Manns MP, Vogel A, Yaqub S, Karlsen TH, Schirmacher P, Boberg KM, Franke A, Roessler S, Folseraas T. Grimsrud MM, et al. Among authors: roessler s. Hepatol Commun. 2024 Jul 5;8(7):e0461. doi: 10.1097/HC9.0000000000000461. eCollection 2024 Jul 1. Hepatol Commun. 2024. PMID: 38967597 Free PMC article.
The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S. Hermanns C, et al. Among authors: roessler s. Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23. Oncogene. 2017. PMID: 28114277
Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC.
Zhou X, An J, Kurilov R, Brors B, Hu K, Peccerella T, Roessler S, Pfütze K, Schulz A, Wolf S, Hohmann N, Theile D, Sauter M, Burhenne J, Ei S, Heger U, Strobel O, Barry ST, Springfeld C, Tjaden C, Bergmann F, Büchler M, Hackert T, Fortunato F, Neoptolemos JP, Bailey P. Zhou X, et al. Among authors: roessler s. Nat Cancer. 2023 Sep;4(9):1362-1381. doi: 10.1038/s43018-023-00628-6. Epub 2023 Sep 7. Nat Cancer. 2023. PMID: 37679568 Free PMC article.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.
Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Among authors: roessler s. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.
LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence.
Konopa A, Meier MA, Franz MJ, Bernardinelli E, Voegele AL, Atreya R, Ribback S, Roessler S, Aigner A, Singer K, Singer S, Sarikas A, Muehlich S. Konopa A, et al. Among authors: roessler s. Oncogenesis. 2022 Dec 28;11(1):69. doi: 10.1038/s41389-022-00445-z. Oncogenesis. 2022. PMID: 36577757 Free PMC article.
Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death.
Rios Garcia M, Meissburger B, Chan J, de Guia RM, Mattijssen F, Roessler S, Birkenfeld AL, Raschzok N, Riols F, Tokarz J, Giroud M, Gil Lozano M, Hartleben G, Nawroth P, Haid M, López M, Herzig S, Berriel Diaz M. Rios Garcia M, et al. Among authors: roessler s. Adv Sci (Weinh). 2022 Oct;9(29):e2104291. doi: 10.1002/advs.202104291. Epub 2022 Aug 28. Adv Sci (Weinh). 2022. PMID: 36031387 Free PMC article.
123 results