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UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.
Elgazzaz M, Lakkappa N, Berdasco C, Mohan UP, Nuzzo A, Restivo L, Martinez A, Scarborough A, Guidry JJ, Sriramula S, Xu J, Daoud H, Mendiola Plá MA, Bowles DE, Beyer AM, Mauvais-Jarvis F, Yue X, Filipeanu CM, Lazartigues E. Elgazzaz M, et al. Hypertension. 2025 Jan;82(1):84-95. doi: 10.1161/HYPERTENSIONAHA.124.23196. Epub 2024 Nov 27. Hypertension. 2025. PMID: 39601126 Free article.
Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE 3rd, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E, Shah SJ, Li Z, Lefer DJ. Doiron JE, et al. Among authors: elgazzaz m. Br J Pharmacol. 2024 Nov;181(21):4294-4310. doi: 10.1111/bph.16493. Epub 2024 Jul 9. Br J Pharmacol. 2024. PMID: 38982742
Upregulation of inflammatory genes and pathways links obesity to severe COVID-19.
Currey J, Ellsworth C, Khatun MS, Wang C, Chen Z, Liu S, Midkiff C, Xiao M, Ren M, Liu F, Elgazzaz M, Fox S, Maness NJ, Rappaport J, Lazartigues E, Blair R, Kolls JK, Mauvais-Jarvis F, Qin X. Currey J, et al. Among authors: elgazzaz m. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167322. doi: 10.1016/j.bbadis.2024.167322. Epub 2024 Jun 26. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38942338 Free PMC article.
UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.
Elgazzaz M, Lakkappa N, Berdasco C, Mohan UP, Nuzzo A, Restivo L, Martinez A, Scarborough A, Guidry JJ, Sriramula S, Xu J, Daoud H, Mendiola Plá MA, Bowles DE, Beyer AM, Mauvais-Jarvis F, Yue X, Filipeanu CM, Lazartigues E. Elgazzaz M, et al. medRxiv [Preprint]. 2024 May 25:2024.05.23.24307722. doi: 10.1101/2024.05.23.24307722. medRxiv. 2024. Update in: Hypertension. 2025 Jan;82(1):84-95. doi: 10.1161/HYPERTENSIONAHA.124.23196 PMID: 38826318 Free PMC article. Updated. Preprint.
Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension.
Mohammed M, Ogunlade B, Elgazzaz M, Berdasco C, Lakkappa N, Ghita I, Guidry JJ, Sriramula S, Xu J, Restivo L, Mendiola Plá MA, Bowles DE, Beyer AM, Yue X, Lazartigues E, Filipeanu CM. Mohammed M, et al. Among authors: elgazzaz m. Cardiovasc Res. 2023 Sep 5;119(11):2130-2141. doi: 10.1093/cvr/cvad070. Cardiovasc Res. 2023. PMID: 37161607 Free PMC article.
13 results