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Discovery of a Pseudomonas aeruginosa-specific small molecule targeting outer membrane protein OprH-LPS interaction by a multiplexed screen.
Poulsen BE, Warrier T, Barkho S, Bagnall J, Romano KP, White T, Yu X, Kawate T, Nguyen PH, Raines K, Ferrara K, Golas AL, FitzGerald M, Boeszoermenyi A, Kaushik V, Serrano-Wu M, Shoresh N, Hung DT. Poulsen BE, et al. Among authors: kaushik v. Cell Chem Biol. 2024 Dec 26:S2451-9456(24)00490-2. doi: 10.1016/j.chembiol.2024.12.001. Online ahead of print. Cell Chem Biol. 2024. PMID: 39732052
Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous recombination.
Deveryshetty J, Mistry A, Pangeni S, Ghoneim M, Tokmina-Lukaszewska M, Kaushik V, Taddei A, Ha T, Bothner B, Antony E. Deveryshetty J, et al. Among authors: kaushik v. bioRxiv [Preprint]. 2024 Nov 7:2024.11.07.622519. doi: 10.1101/2024.11.07.622519. bioRxiv. 2024. PMID: 39574592 Free PMC article. Preprint.
Human hnRNPA1 reorganizes telomere-bound replication protein A.
Granger SL, Sharma R, Kaushik V, Razzaghi M, Honda M, Gaur P, Bhat DS, Labenz SM, Heinen JE, Williams BA, Tabei SMA, Wlodarski MW, Antony E, Spies M. Granger SL, et al. Among authors: kaushik v. Nucleic Acids Res. 2024 Nov 11;52(20):12422-12437. doi: 10.1093/nar/gkae834. Nucleic Acids Res. 2024. PMID: 39329264 Free PMC article.
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models.
Rauh U, Wei G, Serrano-Wu M, Kosmidis G, Kaulfuss S, Siegel F, Thede K, McFarland J, Lemke CT, Werbeck N, Nowak-Reppel K, Pilari S, Menz S, Ocker M, Zhang W, Davis K, Poncet-Montange G, Roth J, Daniels D, Kaushik VK, Hubbard B, Ziegelbauer K, Golub TR. Rauh U, et al. Among authors: kaushik vk. Nat Cancer. 2024 Oct;5(10):1479-1493. doi: 10.1038/s43018-024-00814-0. Epub 2024 Aug 23. Nat Cancer. 2024. PMID: 39179926 Free PMC article.
Unconventional localization of PAI-1 in PML bodies: A possible link with cellular growth of endothelial cells.
Gehlot P, Brünnert D, Kaushik V, Yadav A, Bage S, Gaur K, Saini M, Ehrhardt J, Manjunath GK, Kumar A, Kasliwal N, Sharma AK, Zygmunt M, Goyal P. Gehlot P, et al. Among authors: kaushik v. Biochem Biophys Rep. 2024 Jul 26;39:101793. doi: 10.1016/j.bbrep.2024.101793. eCollection 2024 Sep. Biochem Biophys Rep. 2024. PMID: 39161580 Free PMC article.
438 results