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Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium.
Eng JW, Kato Y, Adachi Y, Swaminathan B, Naiche LA, Vadakath R, Sakamoto Y, Nakazawa Y, Tachino S, Ito K, Abe T, Minoshima Y, Hoshino-Negishi K, Ogasawara H, Kawakatsu T, Nishimura M, Katayama M, Shimizu M, Tahara K, Sato T, Suzuki K, Agarwala K, Iwata M, Nomoto K, Ozawa Y, Imai T, Funahashi Y, Matsui J, Kitajewski J. Eng JW, et al. Among authors: kitajewski j. Cancer Res Commun. 2024 Jul 1;4(7):1881-1893. doi: 10.1158/2767-9764.CRC-24-0081. Cancer Res Commun. 2024. PMID: 38984877 Free PMC article.
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA.
Kleinjan ML, Mao Y, Naiche LA, Joshi JC, Gupta A, Jesse JJ, Shaye DD, Mehta D, Kitajewski J. Kleinjan ML, et al. Among authors: kitajewski j. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1441-1454. doi: 10.1161/ATVBAHA.123.319206. Epub 2023 Jun 15. Arterioscler Thromb Vasc Biol. 2023. PMID: 37317855 Free PMC article.
A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis.
Funahashi Y, Hernandez SL, Das I, Ahn A, Huang J, Vorontchikhina M, Sharma A, Kanamaru E, Borisenko V, Desilva DM, Suzuki A, Wang X, Shawber CJ, Kandel JJ, Yamashiro DJ, Kitajewski J. Funahashi Y, et al. Among authors: kitajewski j. Cancer Res. 2008 Jun 15;68(12):4727-35. doi: 10.1158/0008-5472.CAN-07-6499. Cancer Res. 2008. PMID: 18559519 Free PMC article.
Inactivation of Notch4 Attenuated Pancreatic Tumorigenesis in Mice.
Saeki K, Qiu W, Friedman RA, Pan S, Lu J, Ichimiya S, Chio IIC, Shawber CJ, Kitajewski J, Hu J, Su GH. Saeki K, et al. Among authors: kitajewski j. Cancer Res Commun. 2022 Dec 12;2(12):1601-1616. doi: 10.1158/2767-9764.CRC-22-0106. eCollection 2022 Dec. Cancer Res Commun. 2022. PMID: 36970723 Free PMC article.
Unique functions for Notch4 in murine embryonic lymphangiogenesis.
Muley A, Kim Uh M, Salazar-De Simone G, Swaminathan B, James JM, Murtomaki A, Youn SW, McCarron JD, Kitajewski C, Gnarra Buethe M, Riitano G, Mukouyama YS, Kitajewski J, Shawber CJ. Muley A, et al. Among authors: kitajewski j, kitajewski c. Angiogenesis. 2022 May;25(2):205-224. doi: 10.1007/s10456-021-09822-5. Epub 2021 Oct 19. Angiogenesis. 2022. PMID: 34665379 Free PMC article.
181 results