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Page 1
Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release.
Früh S, Boudkkazi S, Koppensteiner P, Sereikaite V, Chen LY, Fernandez-Fernandez D, Rem PD, Ulrich D, Schwenk J, Chen Z, Le Monnier E, Fritzius T, Innocenti SM, Besseyrias V, Trovò L, Stawarski M, Argilli E, Sherr EH, van Bon B, Kamsteeg EJ, Iascone M, Pilotta A, Cutrì MR, Azamian MS, Hernández-García A, Lalani SR, Rosenfeld JA, Zhao X, Vogel TP, Ona H, Scott DA, Scheiffele P, Strømgaard K, Tafti M, Gassmann M, Fakler B, Shigemoto R, Bettler B. Früh S, et al. Among authors: besseyrias v. Sci Adv. 2024 Jul 12;10(28):eadk5462. doi: 10.1126/sciadv.adk5462. Epub 2024 Jul 10. Sci Adv. 2024. PMID: 38985877 Free PMC article.
Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.
Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, Bildl W, Bentrop D, Staufenbiel M, Gassmann M, Fakler B, Schwenk J, Bettler B. Dinamarca MC, et al. Among authors: besseyrias v. Nat Commun. 2019 Mar 22;10(1):1331. doi: 10.1038/s41467-019-09164-3. Nat Commun. 2019. PMID: 30902970 Free PMC article.
Up-regulation of GABA(B) receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12).
Ivankova K, Turecek R, Fritzius T, Seddik R, Prezeau L, Comps-Agrar L, Pin JP, Fakler B, Besseyrias V, Gassmann M, Bettler B. Ivankova K, et al. Among authors: besseyrias v. J Biol Chem. 2013 Aug 23;288(34):24848-56. doi: 10.1074/jbc.M113.476770. Epub 2013 Jul 10. J Biol Chem. 2013. PMID: 23843457 Free PMC article.
The Sushi domains of GABAB receptors function as axonal targeting signals.
Biermann B, Ivankova-Susankova K, Bradaia A, Abdel Aziz S, Besseyrias V, Kapfhammer JP, Missler M, Gassmann M, Bettler B. Biermann B, et al. Among authors: besseyrias v. J Neurosci. 2010 Jan 27;30(4):1385-94. doi: 10.1523/JNEUROSCI.3172-09.2010. J Neurosci. 2010. PMID: 20107064 Free PMC article.