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Page 1
Galactose-1-phosphate inhibits cytochrome c oxidase and causes mitochondrial dysfunction in classic galactosemia.
Machado CM, de-Souza-Ferreira E, Silva GFS, Pimentel FSA, De-Souza EA, Silva-Rodrigues T, Gandara ACP, Zeidler JD, Fernandes-Siqueira LO, De-Queiroz ALFV, Andrade-Silva L, Victória-Martins K, Fernandes-Carvalho C, Chini EN, Passos JF, Da Poian AT, Montero-Lomelí M, Galina A, Masuda CA. Machado CM, et al. Among authors: de queiroz alfv. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167340. doi: 10.1016/j.bbadis.2024.167340. Epub 2024 Jul 8. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38986816
Sphingolipid depletion suppresses UPR activation and promotes galactose hypersensitivity in yeast models of classic galactosemia.
Pimentel FSA, Machado CM, De-Souza EA, Fernandes CM, De-Queiroz ALFV, Silva GFS, Del Poeta M, Montero-Lomeli M, Masuda CA. Pimentel FSA, et al. Among authors: de queiroz alfv. Biochim Biophys Acta Mol Basis Dis. 2022 Jun 1;1868(6):166389. doi: 10.1016/j.bbadis.2022.166389. Epub 2022 Mar 14. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35301088 Free PMC article.
The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response.
De-Souza EA, Pimentel FSA, De-Queiroz ALFV, Camara H, Felix-Formiga ML, Machado CM, Pinto S, Galina A, Mori MA, Montero-Lomeli M, Masuda CA. De-Souza EA, et al. Among authors: de queiroz alfv. J Biol Chem. 2020 Mar 20;295(12):3773-3782. doi: 10.1074/jbc.RA119.011271. Epub 2020 Jan 29. J Biol Chem. 2020. PMID: 31996377 Free PMC article.