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Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
Kum DB, Vanrusselt H, Acosta Sanchez A, Taverniti V, Verrier ER, Baumert TF, Liu C, Deval J, Corthout N, Munck S, Beigelman L, Blatt LM, Symons JA, Raboisson P, Jekle A, Vendeville S, Debing Y. Kum DB, et al. Among authors: munck s. Hepatology. 2023 Oct 1;78(4):1252-1265. doi: 10.1097/HEP.0000000000000428. Epub 2023 Apr 28. Hepatology. 2023. PMID: 37102495
Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles.
Vanrusselt H, Kum DB, Taverniti V, Liu C, Acosta Sanchez A, Corthout N, Munck S, Baumert TF, Beigelman L, Blatt LM, Symons JA, Deval J, Raboisson P, Verrier ER, Jekle A, Vendeville S, Debing Y. Vanrusselt H, et al. Among authors: munck s. J Virol. 2023 Oct 31;97(10):e0072223. doi: 10.1128/jvi.00722-23. Epub 2023 Sep 27. J Virol. 2023. PMID: 37754761 Free PMC article.
Core facilities coming of age.
Munck S, Anderson KI. Munck S, et al. J Microsc. 2024 Jun;294(3):253-254. doi: 10.1111/jmi.13319. Epub 2024 May 13. J Microsc. 2024. PMID: 38738840 No abstract available.
Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome.
Delafontaine S, Iannuzzo A, Bigley TM, Mylemans B, Rana R, Baatsen P, Poli MC, Rymen D, Jansen K, Mekahli D, Casteels I, Cassiman C, Demaerel P, Lepelley A, Frémond ML, Schrijvers R, Bossuyt X, Vints K, Huybrechts W, Tacine R, Willekens K, Corveleyn A, Boeckx B, Baggio M, Ehlers L, Munck S, Lambrechts D, Voet A, Moens L, Bucciol G, Cooper MA, Davis CM, Delon J, Meyts I. Delafontaine S, et al. Among authors: munck s. J Clin Invest. 2024 Jan 4;134(4):e163604. doi: 10.1172/JCI163604. J Clin Invest. 2024. PMID: 38175705 Free PMC article.
Novel Far-Red Fluorescent 1,4-Dihydropyridines for L-Type Calcium Channel Imaging.
Borgarelli C, Klingl YE, Escamilla-Ayala A, Scarponi C, La Rovere RML, Stoklund Dittlau K, Bultynck G, Sampaolesi M, Schoenberger M, Munck S, Van Den Bosch L, De Borggraeve WM, Ismalaj E. Borgarelli C, et al. Among authors: munck s. J Med Chem. 2024 Oct 24;67(20):18038-18052. doi: 10.1021/acs.jmedchem.4c00565. Epub 2024 Oct 10. J Med Chem. 2024. PMID: 39388369
Staying on track - Keeping things running in a high-end scientific imaging core facility.
Renaud O, Aulner N, Salles A, Halidi N, Brunstein M, Mallet A, Aumayr K, Terjung S, Levy D, Lippens S, Verbavatz JM, Heuser T, Santarella-Mellwig R, Tinevez JY, Woller T, Botzki A, Cawthorne C; Core4Life Consortium; Munck S. Renaud O, et al. Among authors: munck s. J Microsc. 2024 Jun;294(3):276-294. doi: 10.1111/jmi.13304. Epub 2024 Apr 24. J Microsc. 2024. PMID: 38656474 Review.
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