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Targeting apoptotic pathways for cancer therapy.
Tian X, Srinivasan PR, Tajiknia V, Sanchez Sevilla Uruchurtu AF, Seyhan AA, Carneiro BA, De La Cruz A, Pinho-Schwermann M, George A, Zhao S, Strandberg J, Di Cristofano F, Zhang S, Zhou L, Raufi AG, Navaraj A, Zhang Y, Verovkina N, Ghandali M, Ryspayeva D, El-Deiry WS. Tian X, et al. Among authors: srinivasan pr. J Clin Invest. 2024 Jul 15;134(14):e179570. doi: 10.1172/JCI179570. J Clin Invest. 2024. PMID: 39007268 Free PMC article. Review.
Therapeutic targeting of TRAIL death receptors.
Di Cristofano F, George A, Tajiknia V, Ghandali M, Wu L, Zhang Y, Srinivasan P, Strandberg J, Hahn M, Sanchez Sevilla Uruchurtu A, Seyhan AA, Carneiro BA, Zhou L, Huntington KE, El-Deiry WS. Di Cristofano F, et al. Biochem Soc Trans. 2023 Feb 27;51(1):57-70. doi: 10.1042/BST20220098. Biochem Soc Trans. 2023. PMID: 36629496 Free PMC article. Review.
GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer.
Huntington KE, Louie AD, Srinivasan PR, Schorl C, Lu S, Silverberg D, Newhouse D, Wu Z, Zhou L, Borden BA, Giles FJ, Dooner M, Carneiro BA, El-Deiry WS. Huntington KE, et al. Among authors: srinivasan pr. bioRxiv [Preprint]. 2023 Feb 7:2023.02.07.527499. doi: 10.1101/2023.02.07.527499. bioRxiv. 2023. Update in: Int J Mol Sci. 2023 Jun 29;24(13):10870. doi: 10.3390/ijms241310870 PMID: 36798357 Free PMC article. Updated. Preprint.
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer.
Huntington KE, Louie AD, Srinivasan PR, Schorl C, Lu S, Silverberg D, Newhouse D, Wu Z, Zhou L, Borden BA, Giles FJ, Dooner M, Carneiro BA, El-Deiry WS. Huntington KE, et al. Among authors: srinivasan pr. Int J Mol Sci. 2023 Jun 29;24(13):10870. doi: 10.3390/ijms241310870. Int J Mol Sci. 2023. PMID: 37446056 Free PMC article.
Synergistic anti-tumor activity, reduced pERK, and immuno-stimulatory cytokine profiles with 5-FU or ONC212 plus KRAS G12D inhibitor MRTX1133 in CRC and pancreatic cancer cells independent of G12D mutation.
Tajiknia V, Pinho-Schwermann M, Srinivasan PR, Hernandez Borrero L, Zhang L, Huntington KE, El-Deiry WS. Tajiknia V, et al. Among authors: srinivasan pr. Am J Cancer Res. 2024 Sep 15;14(9):4523-4536. doi: 10.62347/DVXL1377. eCollection 2024. Am J Cancer Res. 2024. PMID: 39417197 Free PMC article.
84 results