Pang KS - Search Results

1

After 50 Years of Hepatic Clearance Models, Where Should We Go from Here? Improvements and Implications for Physiologically Based Pharmacokinetic Modeling.

Pang KS, Lu WI, Mulder GJ. Pang KS, et al. Drug Metab Dispos. 2024 Jul 16;52(8):919-931. doi: 10.1124/dmd.124.001649. Drug Metab Dispos. 2024. PMID: 39013583

2

The effect of hepatic blood flow on formation of metabolites.

Pang KS, Mulder GJ. Pang KS, et al. Drug Metab Dispos. 1990 May-Jun;18(3):270-5. Drug Metab Dispos. 1990. PMID: 1974185 Review. No abstract available.

3

Localization of glutathione conjugation activities toward bromosulfophthalein in perfused rat liver. Studies with the multiple indicator dilution technique.

Zhao Y, Snel CA, Mulder GJ, Pang KS. Zhao Y, et al. Among authors: pang ks. Drug Metab Dispos. 1993 Nov-Dec;21(6):1070-8. Drug Metab Dispos. 1993. PMID: 7905386

4

Stereoselectivity of glutathione conjugation in vivo, in the perfused liver and in isolated hepatocytes.

Mulder GJ, te Koppele JM, Schipper CG, Snel WH, Pang KS, Polhuijs M. Mulder GJ, et al. Among authors: pang ks. Drug Metab Rev. 1991;23(3-4):311-30. doi: 10.3109/03602539109029762. Drug Metab Rev. 1991. PMID: 1935574 Review. No abstract available.

5

Inhibition of glutathione conjugation by glutathione analogues in the perfused rat liver. Effect of esterification on the potency of gamma-L-glutamyl-alpha-(D-2-aminoadipyl)-N-2-heptylamine.

Ouwerkerk-Mahadevan S, Tirona RG, Ripping RA, Ploemen JH, van Bladeren PJ, Pang KS, van Boom JH, Mulder GJ. Ouwerkerk-Mahadevan S, et al. Among authors: pang ks. Drug Metab Dispos. 1997 Oct;25(10):1137-43. Drug Metab Dispos. 1997. PMID: 9321516

6

Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.

Yang QJ, Fan J, Chen S, Liu L, Sun H, Pang KS. Yang QJ, et al. Among authors: pang ks. Drug Metab Dispos. 2016 Jul;44(7):1123-38. doi: 10.1124/dmd.116.069542. Epub 2016 Apr 20. Drug Metab Dispos. 2016. PMID: 27098743

7

Stereoselective glutathione conjugation and amidase-catalyzed hydrolysis of alpha-bromoisovalerylurea enantiomers in isolated rat hepatocytes.

te Koppele JM, de Lannoy IA, Pang KS, Mulder GJ. te Koppele JM, et al. Among authors: pang ks. J Pharmacol Exp Ther. 1987 Oct;243(1):349-55. J Pharmacol Exp Ther. 1987. PMID: 3668862

8

Inhibition of acetaminophen sulfation by 2,6-dichloro-4-nitrophenol in the perfused rat liver preparation. Lack of a compensatory increase of glucuronidation.

Fayz S, Cherry WF, Dawson JR, Mulder GJ, Pang KS. Fayz S, et al. Among authors: pang ks. Drug Metab Dispos. 1984 May-Jun;12(3):323-9. Drug Metab Dispos. 1984. PMID: 6145559

9

Glutathione conjugation of bromosulfophthalein in relation to hepatic glutathione content in the rat in vivo and in the perfused rat liver.

Snel CA, Pang KS, Mulder GJ. Snel CA, et al. Among authors: pang ks. Hepatology. 1995 May;21(5):1387-94. doi: 10.1016/0270-9139(95)90061-6. Hepatology. 1995. PMID: 7737646

10

Stereoselectivity in glutathione conjugation and amidase-catalyzed hydrolysis of the 2-bromoisovalerylurea enantiomers in the single-pass perfused rat liver.

Polhuijs M, Gasinska I, Cherry WF, Mulder GJ, Pang KS. Polhuijs M, et al. Among authors: pang ks. J Pharmacol Exp Ther. 1993 Jun;265(3):1406-12. J Pharmacol Exp Ther. 1993. PMID: 8510017

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