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HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy.
Galvez NMS, Cao Y, Nitido AD, Deal CE, Boutros CL, MacDonald SW, Albrecht YES, Lam EC, Sheehan ML, Parsons D, Lin AZ, Deymier MJ, Brady JM, Moon B, Bullock CB, Tanno S, Pegu A, Chen X, Liu C, Koup RA, Mascola JR, Vrbanac VD, Lingwood D, Balazs AB. Galvez NMS, et al. Among authors: lingwood d. bioRxiv [Preprint]. 2024 Jul 13:2024.07.11.603156. doi: 10.1101/2024.07.11.603156. bioRxiv. 2024. PMID: 39026699 Free PMC article. Preprint.
Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation.
Hauser BM, Sangesland M, Lam EC, Denis KJS, Sheehan ML, Vu ML, Cheng AH, Balazs AB, Lingwood D, Schmidt AG. Hauser BM, et al. Among authors: lingwood d. bioRxiv [Preprint]. 2023 Aug 22:2023.08.21.554179. doi: 10.1101/2023.08.21.554179. bioRxiv. 2023. Update in: ACS Infect Dis. 2024 Feb 9;10(2):553-561. doi: 10.1021/acsinfecdis.3c00483 PMID: 37662405 Free PMC article. Updated. Preprint.
Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif.
Hauser BM, Sangesland M, Denis KJS, Windsor IW, Feldman J, Lam EC, Kannegieter T, Balazs AB, Lingwood D, Schmidt AG. Hauser BM, et al. Among authors: lingwood d. bioRxiv [Preprint]. 2021 Jul 9:2021.03.15.435440. doi: 10.1101/2021.03.15.435440. bioRxiv. 2021. Update in: Cell Rep. 2022 Mar 22;38(12):110561. doi: 10.1016/j.celrep.2022.110561 PMID: 33758851 Free PMC article. Updated. Preprint.
Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds.
Wamhoff EC, Ronsard L, Feldman J, Knappe GA, Hauser BM, Romanov A, Lam E, Denis KS, Boucau J, Barczak AK, Balazs AB, Schmidt A, Lingwood D, Bathe M. Wamhoff EC, et al. Among authors: lingwood d. bioRxiv [Preprint]. 2023 Jun 19:2022.08.16.504128. doi: 10.1101/2022.08.16.504128. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 30;15(1):795. doi: 10.1038/s41467-024-44869-0 PMID: 36032975 Free PMC article. Updated. Preprint.
COVID-19 neutralizing antibodies predict disease severity and survival.
Garcia-Beltran WF, Lam EC, Astudillo MG, Yang D, Miller TE, Feldman J, Hauser BM, Caradonna TM, Clayton KL, Nitido AD, Murali MR, Alter G, Charles RC, Dighe A, Branda JA, Lennerz JK, Lingwood D, Schmidt AG, Iafrate AJ, Balazs AB. Garcia-Beltran WF, et al. Among authors: lingwood d. medRxiv [Preprint]. 2020 Oct 20:2020.10.15.20213512. doi: 10.1101/2020.10.15.20213512. medRxiv. 2020. Update in: Cell. 2021 Jan 21;184(2):476-488.e11. doi: 10.1016/j.cell.2020.12.015 PMID: 33106822 Free PMC article. Updated. Preprint.
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses.
Feldman J, Bals J, Altomare CG, St Denis K, Lam EC, Hauser BM, Ronsard L, Sangesland M, Moreno TB, Okonkwo V, Hartojo N, Balazs AB, Bajic G, Lingwood D, Schmidt AG. Feldman J, et al. Among authors: lingwood d. bioRxiv [Preprint]. 2021 Jul 9:2021.02.02.429458. doi: 10.1101/2021.02.02.429458. bioRxiv. 2021. Update in: Sci Immunol. 2021 Dec 10;6(66):eabl5842. doi: 10.1126/sciimmunol.abl5842 PMID: 33594359 Free PMC article. Updated. Preprint.
COVID-19-neutralizing antibodies predict disease severity and survival.
Garcia-Beltran WF, Lam EC, Astudillo MG, Yang D, Miller TE, Feldman J, Hauser BM, Caradonna TM, Clayton KL, Nitido AD, Murali MR, Alter G, Charles RC, Dighe A, Branda JA, Lennerz JK, Lingwood D, Schmidt AG, Iafrate AJ, Balazs AB. Garcia-Beltran WF, et al. Among authors: lingwood d. Cell. 2021 Jan 21;184(2):476-488.e11. doi: 10.1016/j.cell.2020.12.015. Epub 2020 Dec 15. Cell. 2021. PMID: 33412089 Free PMC article.
77 results