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Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.
Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P. Zhang P, et al. Among authors: lu m. Cell Rep. 2024 Aug 27;43(8):114518. doi: 10.1016/j.celrep.2024.114518. Epub 2024 Jul 18. Cell Rep. 2024. PMID: 39028623 Free PMC article.
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.
Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W. Lu M, et al. Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10. Nature. 2019. PMID: 30971821 Free PMC article.
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.
Henderson R, Lu M, Zhou Y, Mu Z, Parks R, Han Q, Hsu AL, Carter E, Blanchard SC, Edwards RJ, Wiehe K, Saunders KO, Borgnia MJ, Bartesaghi A, Mothes W, Haynes BF, Acharya P, Munir Alam S. Henderson R, et al. Among authors: lu m. Nat Commun. 2020 Jan 24;11(1):520. doi: 10.1038/s41467-019-14196-w. Nat Commun. 2020. PMID: 31980614 Free PMC article.
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins.
Zou S, Zhang S, Gaffney A, Ding H, Lu M, Grover JR, Farrell M, Nguyen HT, Zhao C, Anang S, Zhao M, Mohammadi M, Blanchard SC, Abrams C, Madani N, Mothes W, Kappes JC, Smith AB 3rd, Sodroski J. Zou S, et al. Among authors: lu m. J Virol. 2020 May 4;94(10):e00148-20. doi: 10.1128/JVI.00148-20. Print 2020 May 4. J Virol. 2020. PMID: 32161177 Free PMC article.
Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles.
Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prevost J, Beaudoin-Bussieres G, Anand SP, Laumaea A, Grover JR, Lihong L, Ho DD, Mascola J, Finzi A, Kwong PD, Blanchard SC, Mothes W. Lu M, et al. bioRxiv [Preprint]. 2020 Sep 13:2020.09.10.286948. doi: 10.1101/2020.09.10.286948. bioRxiv. 2020. Update in: Cell Host Microbe. 2020 Dec 9;28(6):880-891.e8. doi: 10.1016/j.chom.2020.11.001 PMID: 32935100 Free PMC article. Updated. Preprint.
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