Mizuguchi M - Search Results

1

Structural insights into rapamycin-induced oligomerization of a FRB-FKBP fusion protein.

Inobe T, Sakaguchi R, Obita T, Mukaiyama A, Koike S, Yokoyama T, Mizuguchi M, Akiyama S. Inobe T, et al. Among authors: mizuguchi m. FEBS Lett. 2024 Sep;598(18):2292-2305. doi: 10.1002/1873-3468.14986. Epub 2024 Jul 19. FEBS Lett. 2024. PMID: 39031920

2

Quaternary structure, aggregation and cytotoxicity of transthyretin.

Mizuguchi M, Yokoyama T, Nabeshima Y, Kawano K, Tanaka I, Niimura N. Mizuguchi M, et al. Amyloid. 2012 Jun;19 Suppl 1:5-7. doi: 10.3109/13506129.2012.666510. Epub 2012 Mar 23. Amyloid. 2012. PMID: 22439750

3

Hydrogen-bond network and pH sensitivity in human transthyretin.

Yokoyama T, Mizuguchi M, Nabeshima Y, Kusaka K, Yamada T, Hosoya T, Ohhara T, Kurihara K, Tanaka I, Niimura N. Yokoyama T, et al. Among authors: mizuguchi m. J Synchrotron Radiat. 2013 Nov;20(Pt 6):834-7. doi: 10.1107/S090904951302075X. Epub 2013 Sep 29. J Synchrotron Radiat. 2013. PMID: 24121323 Free PMC article.

4

Crystal structures of human transthyretin complexed with glabridin.

Yokoyama T, Kosaka Y, Mizuguchi M. Yokoyama T, et al. Among authors: mizuguchi m. J Med Chem. 2014 Feb 13;57(3):1090-6. doi: 10.1021/jm401832j. Epub 2014 Jan 23. J Med Chem. 2014. PMID: 24422526

5

Crystallization and preliminary neutron diffraction experiment of human farnesyl pyrophosphate synthase complexed with risedronate.

Yokoyama T, Ostermann A, Mizuguchi M, Niimura N, Schrader TE, Tanaka I. Yokoyama T, et al. Among authors: mizuguchi m. Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):470-2. doi: 10.1107/S2053230X14004087. Epub 2014 Mar 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24699741 Free PMC article.

6

Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kD.

Mizuguchi M, Obita T, Serita T, Kojima R, Nabeshima Y, Okazawa H. Mizuguchi M, et al. Nat Commun. 2014 Apr 30;5:3822. doi: 10.1038/ncomms4822. Nat Commun. 2014. PMID: 24781215 Free article.

7

Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1.

Mizuguchi M, Fuju T, Obita T, Ishikawa M, Tsuda M, Tabuchi A. Mizuguchi M, et al. Sci Rep. 2014 Jun 9;4:5224. doi: 10.1038/srep05224. Sci Rep. 2014. PMID: 24909411 Free PMC article.

8

In silico and pharmacological screenings identify novel serine racemase inhibitors.

Mori H, Wada R, Li J, Ishimoto T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N. Mori H, et al. Among authors: mizuguchi m. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3732-5. doi: 10.1016/j.bmcl.2014.07.003. Epub 2014 Jul 5. Bioorg Med Chem Lett. 2014. PMID: 25066953

9

Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.

Yokoyama T, Kosaka Y, Mizuguchi M. Yokoyama T, et al. Among authors: mizuguchi m. J Med Chem. 2014 Nov 13;57(21):8928-35. doi: 10.1021/jm500997m. Epub 2014 Oct 20. J Med Chem. 2014. PMID: 25314129

10

Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.

Yokoyama T, Ueda M, Ando Y, Mizuguchi M. Yokoyama T, et al. Among authors: mizuguchi m. Sci Rep. 2015 Aug 27;5:13570. doi: 10.1038/srep13570. Sci Rep. 2015. PMID: 26310724 Free PMC article.

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