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Enhancing the antischistosomal activity of carvacryl acetate using nanoemulsion.
de Souza RL, Mengarda AC, Roquini DB, Melo CO, de Morais MC, C Espírito-Santo MC, de Sousa DP, Moraes J, Oliveira EE. de Souza RL, et al. Among authors: roquini db. Nanomedicine (Lond). 2023 Feb;18(4):331-342. doi: 10.2217/nnm-2022-0228. Epub 2023 May 4. Nanomedicine (Lond). 2023. PMID: 37140262
H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies.
Xavier RP, Mengarda AC, Silva MP, Roquini DB, Salvadori MC, Teixeira FS, Pinto PL, Morais TR, Ferreira LLG, Andricopulo AD, de Moraes J. Xavier RP, et al. Among authors: roquini db. Parasit Vectors. 2020 Jun 1;13(1):278. doi: 10.1186/s13071-020-04140-z. Parasit Vectors. 2020. PMID: 32487175 Free PMC article.
Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model.
Roquini DB, Cogo RM, Mengarda AC, Mazloum SF, Morais CS, Xavier RP, Salvadori MC, Teixeira FS, Ferreira LE, Pinto PL, Morais TR, de Moraes J. Roquini DB, et al. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01208-19. doi: 10.1128/AAC.01208-19. Epub 2019 Sep 16. Antimicrob Agents Chemother. 2019. PMID: 31527034 Free PMC article.
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