Cortez LM - Search Results

1

Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders.

Flores-Fernandez JM, Pesch V, Sriraman A, Chimal-Juarez E, Amidian S, Wang X, Duckering C, Fang A, Reithofer S, Ma L, Cortez LM, Sim VL, Tamgüney G, Wille H. Flores-Fernandez JM, et al. Among authors: cortez lm. Bioeng Transl Med. 2024 Apr 9;9(4):e10665. doi: 10.1002/btm2.10665. eCollection 2024 Jul. Bioeng Transl Med. 2024. PMID: 39036077 Free PMC article.

2

The therapeutic potential of chemical chaperones in protein folding diseases.

Cortez L, Sim V. Cortez L, et al. Prion. 2014 Mar-Apr;8(2):197-202. doi: 10.4161/pri.28938. Epub 2014 May 12. Prion. 2014. PMID: 24818993 Free PMC article. Review.

3

Implications of prion polymorphisms.

Cortez LM, Sim VL. Cortez LM, et al. Prion. 2013 Jul-Aug;7(4):276-9. doi: 10.4161/pri.25566. Epub 2013 Jun 27. Prion. 2013. PMID: 23807178 Free PMC article. Review.

4

Native nanodiscs formed by styrene maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids.

Esmaili M, Tancowny BP, Wang X, Moses A, Cortez LM, Sim VL, Wille H, Overduin M. Esmaili M, et al. Among authors: cortez lm. J Biol Chem. 2020 Jun 19;295(25):8460-8469. doi: 10.1074/jbc.RA119.012348. Epub 2020 May 1. J Biol Chem. 2020. PMID: 32358064 Free PMC article.

5

Asymmetric-flow field-flow fractionation of prions reveals a strain-specific continuum of quaternary structures with protease resistance developing at a hydrodynamic radius of 15 nm.

Cortez LM, Nemani SK, Duque Velásquez C, Sriraman A, Wang Y, Wille H, McKenzie D, Sim VL. Cortez LM, et al. PLoS Pathog. 2021 Jun 28;17(6):e1009703. doi: 10.1371/journal.ppat.1009703. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34181702 Free PMC article.

6

Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology.

Wu Q, Cortez L, Kamali-Jamil R, Sim V, Wille H, Kar S. Wu Q, et al. Dis Model Mech. 2021 Oct 1;14(10):dmm048929. doi: 10.1242/dmm.048929. Epub 2021 Oct 26. Dis Model Mech. 2021. PMID: 34524402 Free PMC article.

7

Mouse prion protein polymorphism Phe-108/Val-189 affects the kinetics of fibril formation and the response to seeding: evidence for a two-step nucleation polymerization mechanism.

Cortez LM, Kumar J, Renault L, Young HS, Sim VL. Cortez LM, et al. J Biol Chem. 2013 Feb 15;288(7):4772-81. doi: 10.1074/jbc.M112.414581. Epub 2013 Jan 2. J Biol Chem. 2013. PMID: 23283973 Free PMC article.

8

Toll-like receptor-mediated immune response inhibits prion propagation.

Kang SG, Kim C, Cortez LM, Carmen Garza M, Yang J, Wille H, Sim VL, Westaway D, McKenzie D, Aiken J. Kang SG, et al. Among authors: cortez lm. Glia. 2016 Jun;64(6):937-51. doi: 10.1002/glia.22973. Epub 2016 Feb 16. Glia. 2016. PMID: 26880394

9

Pharmacological chaperone reshapes the energy landscape for folding and aggregation of the prion protein.

Gupta AN, Neupane K, Rezajooei N, Cortez LM, Sim VL, Woodside MT. Gupta AN, et al. Among authors: cortez lm. Nat Commun. 2016 Jun 27;7:12058. doi: 10.1038/ncomms12058. Nat Commun. 2016. PMID: 27346148 Free PMC article.

10

Probing the origin of prion protein misfolding via reconstruction of ancestral proteins.

Cortez LM, Morrison AJ, Garen CR, Patterson S, Uyesugi T, Petrosyan R, Sekar RV, Harms MJ, Woodside MT, Sim VL. Cortez LM, et al. Protein Sci. 2022 Dec;31(12):e4477. doi: 10.1002/pro.4477. Protein Sci. 2022. PMID: 36254680 Free PMC article.

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