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Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4.
Mizunuma M, Redon CE, Saha LK, Tran AD, Dhall A, Sebastian R, Taniyama D, Kruhlak MJ, Reinhold WC, Takebe N, Pommier Y. Mizunuma M, et al. Among authors: redon ce. Cancer Res Commun. 2024 Aug 1;4(8):2101-2111. doi: 10.1158/2767-9764.CRC-24-0093. Cancer Res Commun. 2024. PMID: 39041239 Free PMC article.
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.
Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, Sedelnikova OA, Pilch DR, Rogakou EP, Celeste A, Chen HT, Nussenzweig A, Aladjem MI, Bonner WM, Pommier Y. Furuta T, et al. J Biol Chem. 2003 May 30;278(22):20303-12. doi: 10.1074/jbc.M300198200. Epub 2003 Mar 25. J Biol Chem. 2003. PMID: 12660252 Free article.
Repair of topoisomerase I-mediated DNA damage.
Pommier Y, Barcelo JM, Rao VA, Sordet O, Jobson AG, Thibaut L, Miao ZH, Seiler JA, Zhang H, Marchand C, Agama K, Nitiss JL, Redon C. Pommier Y, et al. Prog Nucleic Acid Res Mol Biol. 2006;81:179-229. doi: 10.1016/S0079-6603(06)81005-6. Prog Nucleic Acid Res Mol Biol. 2006. PMID: 16891172 Free PMC article. Review.
GammaH2AX and cancer.
Bonner WM, Redon CE, Dickey JS, Nakamura AJ, Sedelnikova OA, Solier S, Pommier Y. Bonner WM, et al. Among authors: redon ce. Nat Rev Cancer. 2008 Dec;8(12):957-67. doi: 10.1038/nrc2523. Epub 2008 Nov 13. Nat Rev Cancer. 2008. PMID: 19005492 Free PMC article. Review.
100 results