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Page 1
A ligand discovery toolbox for the WWE domain family of human E3 ligases.
Münzker L, Kimani SW, Fowkes MM, Dong A, Zheng H, Li Y, Dasovich M, Zak KM, Leung AKL, Elkins JM, Kessler D, Arrowsmith CH, Halabelian L, Böttcher J. Münzker L, et al. Among authors: zak km. Commun Biol. 2024 Jul 24;7(1):901. doi: 10.1038/s42003-024-06584-w. Commun Biol. 2024. PMID: 39048679 Free PMC article.
Ligandability assessment of the C-terminal Rel-homology domain of NFAT1.
Böttcher J, Fuchs JE, Mayer M, Kahmann J, Zak KM, Wunberg T, Woehrle S, Kessler D. Böttcher J, et al. Among authors: zak km. Arch Pharm (Weinheim). 2024 Jun;357(6):e2300649. doi: 10.1002/ardp.202300649. Epub 2024 Feb 23. Arch Pharm (Weinheim). 2024. PMID: 38396281
Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays.
Gerstberger T, Berger H, Büttner FH, Gmachl M, Kessler D, Koegl M, Lucas S, Martin LJ, Mayer M, McConnell DB, Mitzner S, Scholz G, Treu M, Wolkerstorfer B, Zahn S, Zak KM, Jaeger PA, Ettmayer P. Gerstberger T, et al. Among authors: zak km. J Med Chem. 2024 Jul 25;67(14):11701-11711. doi: 10.1021/acs.jmedchem.3c02381. Epub 2024 Jul 15. J Med Chem. 2024. PMID: 39009041
NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J. Biebl MM, et al. Among authors: zak km. Mol Cell. 2022 Feb 3;82(3):555-569.e7. doi: 10.1016/j.molcel.2021.12.031. Epub 2022 Jan 20. Mol Cell. 2022. PMID: 35063133 Free article.
Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
Borchard S, Raschke S, Zak KM, Eberhagen C, Einer C, Weber E, Müller SM, Michalke B, Lichtmannegger J, Wieser A, Rieder T, Popowicz GM, Adamski J, Klingenspor M, Coles AH, Viana R, Vendelbo MH, Sandahl TD, Schwerdtle T, Plitz T, Zischka H. Borchard S, et al. Among authors: zak km. Life Sci Alliance. 2021 Dec 2;5(3):e202101164. doi: 10.26508/lsa.202101164. Print 2022 Mar. Life Sci Alliance. 2021. PMID: 34857647 Free PMC article.
Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase.
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM. Softley CA, et al. Among authors: zak km. Antimicrob Agents Chemother. 2020 May 21;64(6):e00123-20. doi: 10.1128/AAC.00123-20. Print 2020 May 21. Antimicrob Agents Chemother. 2020. PMID: 32205343 Free PMC article.
21 results