Luthman K - Search Results

1

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites.

Ndreu L, Carlsson J, Ponting DJ, Niklasson IB, Stéen EJL, McHugh L, O'Boyle NM, Luthman K, Karlberg AT, Karlsson I. Ndreu L, et al. Among authors: luthman k. Front Toxicol. 2024 Jul 10;6:1398852. doi: 10.3389/ftox.2024.1398852. eCollection 2024. Front Toxicol. 2024. PMID: 39050368 Free PMC article.

2

Bioactivation of cinnamic alcohol forms several strong skin sensitizers.

Niklasson IB, Ponting DJ, Luthman K, Karlberg AT. Niklasson IB, et al. Among authors: luthman k. Chem Res Toxicol. 2014 Apr 21;27(4):568-75. doi: 10.1021/tx400428f. Epub 2014 Feb 7. Chem Res Toxicol. 2014. PMID: 24460212

3

Epoxy resin monomers with reduced skin sensitizing potency.

O'Boyle NM, Niklasson IB, Tehrani-Bagha AR, Delaine T, Holmberg K, Luthman K, Karlberg AT. O'Boyle NM, et al. Among authors: luthman k. Chem Res Toxicol. 2014 Jun 16;27(6):1002-10. doi: 10.1021/tx5000624. Epub 2014 Jun 2. Chem Res Toxicol. 2014. PMID: 24830866

4

Epoxyalcohols: bioactivation and conjugation required for skin sensitization.

Delaine T, Ponting DJ, Niklasson IB, Emter R, Hagvall L, Norrby PO, Natsch A, Luthman K, Karlberg AT. Delaine T, et al. Among authors: luthman k. Chem Res Toxicol. 2014 Oct 20;27(10):1860-70. doi: 10.1021/tx500297d. Epub 2014 Sep 22. Chem Res Toxicol. 2014. PMID: 25195701

5

Nature-Derived Epoxy Resin Monomers with Reduced Sensitizing Capacity─Isosorbide-Based Bis-Epoxides.

Karlsson I, Ponting DJ, Ortega MA, Niklasson IB, Ndreu L, Stéen EJL, Seifert T, Luthman K, Karlberg AT. Karlsson I, et al. Among authors: luthman k. Chem Res Toxicol. 2023 Feb 20;36(2):281-290. doi: 10.1021/acs.chemrestox.2c00347. Epub 2023 Jan 18. Chem Res Toxicol. 2023. PMID: 36652206 Free PMC article.

6

A conjugated diene identified as a prohapten: contact allergenic activity and chemical reactivity of proposed epoxide metabolites.

Nilsson AM, Bergström MA, Luthman K, Nilsson JL, Karlberg AT. Nilsson AM, et al. Among authors: luthman k. Chem Res Toxicol. 2005 Feb;18(2):308-16. doi: 10.1021/tx049758c. Chem Res Toxicol. 2005. PMID: 15720137

7

An alpha,beta-unsaturated oxime identified as a strong contact allergen. Indications of antigen formation via several pathways.

Nilsson AM, Bergström MA, Luthman K, Nilsson JL, Karlberg AT. Nilsson AM, et al. Among authors: luthman k. Food Chem Toxicol. 2005 Nov;43(11):1627-36. doi: 10.1016/j.fct.2005.05.004. Food Chem Toxicol. 2005. PMID: 15978713

8

Conjugated dienes as prohaptens in contact allergy: in vivo and in vitro studies of structure-activity relationships, sensitizing capacity, and metabolic activation.

Bergström MA, Luthman K, Nilsson JL, Karlberg AT. Bergström MA, et al. Among authors: luthman k. Chem Res Toxicol. 2006 Jun;19(6):760-9. doi: 10.1021/tx060006n. Chem Res Toxicol. 2006. PMID: 16780354

9

Metabolic epoxidation of an alpha,beta-unsaturated oxime generates sensitizers of extreme potency. Are nitroso intermediates responsible?

Bergström MA, Luthman K, Karlberg AT. Bergström MA, et al. Among authors: luthman k. Chem Res Toxicol. 2007 Jun;20(6):927-36. doi: 10.1021/tx7000114. Epub 2007 May 19. Chem Res Toxicol. 2007. PMID: 17511479

10

Allergic contact dermatitis--formation, structural requirements, and reactivity of skin sensitizers.

Karlberg AT, Bergström MA, Börje A, Luthman K, Nilsson JL. Karlberg AT, et al. Among authors: luthman k. Chem Res Toxicol. 2008 Jan;21(1):53-69. doi: 10.1021/tx7002239. Epub 2007 Dec 4. Chem Res Toxicol. 2008. PMID: 18052130 Review.

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