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Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites.
Trotta AM, Tomassi S, Di Maiolo G, Ieranò C, Vetrei C, D'Alterio C, Merlino F, Messere A, D'Aniello A, Del Bene A, Mazzarella V, Roggia M, Natale B, Cutolo R, Campagna E, Mottola S, Russo R, Chambery A, Benedetti R, Altucci L, Cosconati S, Scala S, Di Maro S. Trotta AM, et al. Among authors: russo r. Eur J Med Chem. 2024 Oct 5;276:116669. doi: 10.1016/j.ejmech.2024.116669. Epub 2024 Jul 14. Eur J Med Chem. 2024. PMID: 39053189
Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers.
Tomassi S, Ieranò C, Mercurio ME, Nigro E, Daniele A, Russo R, Chambery A, Baglivo I, Pedone PV, Rea G, Napolitano M, Scala S, Cosconati S, Marinelli L, Novellino E, Messere A, Di Maro S. Tomassi S, et al. Among authors: russo r. Bioorg Med Chem. 2018 May 15;26(9):2539-2550. doi: 10.1016/j.bmc.2018.04.017. Epub 2018 Apr 7. Bioorg Med Chem. 2018. PMID: 29656988
Ultrasound-assisted Peptide Nucleic Acids synthesis (US-PNAS).
Del Bene A, D'Aniello A, Tomassi S, Merlino F, Mazzarella V, Russo R, Chambery A, Cosconati S, Di Maro S, Messere A. Del Bene A, et al. Among authors: russo r. Ultrason Sonochem. 2023 May;95:106360. doi: 10.1016/j.ultsonch.2023.106360. Epub 2023 Mar 8. Ultrason Sonochem. 2023. PMID: 36913782 Free PMC article.
Tailoring the Structure of Cell Penetrating DNA and RNA Binding Nucleopeptides.
Tomassi S, Ieranò C, Del Bene A, D'Aniello A, Napolitano M, Rea G, Auletta F, Portella L, Capiluongo A, Mazzarella V, Russo R, Chambery A, Scala S, Di Maro S, Messere A. Tomassi S, et al. Among authors: russo r. Int J Mol Sci. 2022 Jul 31;23(15):8504. doi: 10.3390/ijms23158504. Int J Mol Sci. 2022. PMID: 35955638 Free PMC article.
Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.
Sobinoff AP, Di Maro S, Low RRJ, Benedetti R, Tomassi S, D'Aniello A, Russo R, Baglivo I, Chianese U, Pedone PV, Chambery A, Cesare AJ, Altucci L, Pickett HA, Cosconati S. Sobinoff AP, et al. Among authors: russo r. Cell Chem Biol. 2023 Dec 21;30(12):1652-1665.e6. doi: 10.1016/j.chembiol.2023.11.008. Epub 2023 Dec 7. Cell Chem Biol. 2023. PMID: 38065101 Free article.
2,200 results