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755 results

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Page 1
Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates.
Buckley M, Araínga M, Maiorino L, Pires IS, Kim BJ, Michaels KK, Dye J, Qureshi K, Zhang Y, Mak H, Steichen JM, Schief WR, Villinger F, Irvine DJ. Buckley M, et al. Among authors: irvine dj. Mol Ther. 2025 Jan 9:S1525-0016(25)00012-7. doi: 10.1016/j.ymthe.2025.01.008. Online ahead of print. Mol Ther. 2025. PMID: 39797396 Free article.
Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle.
Yousefpour P, Zhang YJ, Maiorino L, Melo MB, Arainga Ramirez MA, Kumarapperuma SC, Xiao P, Silva M, Li N, Michaels KK, Georgeson E, Eskandarzadeh S, Kubitz M, Groschel B, Qureshi K, Fontenot J, Hangartner L, Nedellec R, Love JC, Burton DR, Schief WR, Villinger FJ, Irvine DJ. Yousefpour P, et al. Among authors: irvine dj. PNAS Nexus. 2024 Nov 25;3(12):pgae529. doi: 10.1093/pnasnexus/pgae529. eCollection 2024 Dec. PNAS Nexus. 2024. PMID: 39677368 Free PMC article.
Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques.
Pratap PP, Cottrell CA, Quinn J, Carnathan DG, Bader DLV, Tran AS, Enemuo CA, Ngo JT, Richey ST, Gao H, Shen X, Greene KM, Hurtado J, Michaels KK, Ben-Akiva E, Allen JD, Ozorowski G, Crispin M, Briney B, Montefiori D, Silvestri G, Irvine DJ, Crotty S, Ward AB. Pratap PP, et al. Among authors: irvine dj. bioRxiv [Preprint]. 2024 Nov 29:2024.11.27.625755. doi: 10.1101/2024.11.27.625755. bioRxiv. 2024. PMID: 39651156 Free PMC article. Preprint.
Diverse priming outcomes under conditions of very rare precursor B cells.
Madden PJ, Marina-Zárate E, Rodrigues KA, Steichen JM, Shil M, Ni K, Michaels KK, Maiorino L, Upadhyay AA, Saha S, Pradhan A, Kalyuzhiny O, Liguori A, Lopez PG, Phung I, Phelps N, Georgeson E, Alavi N, Kubitz M, Lu D, Eskandarzadeh S, Metz A, Rodriguez OL, Shields K, Schultze S, Smith ML, Healy BS, Lim D, Lewis VR, Ben-Akiva E, Pinney W, Gregory J, Xiao S, Carnathan DG, Kasturi SP, Watson CT, Bosinger SE, Silvestri G, Schief WR, Irvine DJ, Crotty S. Madden PJ, et al. Among authors: irvine dj. bioRxiv [Preprint]. 2024 Nov 25:2024.11.21.624746. doi: 10.1101/2024.11.21.624746. bioRxiv. 2024. PMID: 39651117 Free PMC article. Preprint.
Charge-Stabilized Nanodiscs as a New Class of Lipid Nanoparticles.
Pires IS, Hostetler A, Covarrubias G, Carlo IS, Suggs JR, Kim BJ, Pickering AJ, Gordon E, Irvine DJ, Hammond PT. Pires IS, et al. Among authors: irvine dj. Adv Mater. 2024 Dec;36(52):e2408307. doi: 10.1002/adma.202408307. Epub 2024 Nov 14. Adv Mater. 2024. PMID: 39543433 Free PMC article.
TRBC1-CAR T cell therapy in peripheral T cell lymphoma: a phase 1/2 trial.
Cwynarski K, Iacoboni G, Tholouli E, Menne T, Irvine DA, Balasubramaniam N, Wood L, Shang J, Xue E, Zhang Y, Basilico S, Neves M, Raymond M, Scott I, El-Kholy M, Jha R, Dainton-Smith H, Hussain R, Day W, Ferrari M, Thomas S, Lilova K, Brugger W, Marafioti T, Lao-Sirieix P, Maciocia P, Pule M. Cwynarski K, et al. Among authors: irvine da. Nat Med. 2025 Jan;31(1):137-143. doi: 10.1038/s41591-024-03326-7. Epub 2024 Nov 11. Nat Med. 2025. PMID: 39528665 Free PMC article. Clinical Trial.
755 results