Wang H - Search Results

1

MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read-Through Transcription and Intragenic Contacts.

Wang H, Ma B, Stevens T, Knapp J, Lu J, Prochownik EV. Wang H, et al. bioRxiv [Preprint]. 2024 Jul 16:2024.07.11.603118. doi: 10.1101/2024.07.11.603118. bioRxiv. 2024. PMID: 39071289 Free PMC article. Preprint.

2

The Myc-Like Mlx Network Impacts Aging and Metabolism.

Wang H, Stevens T, Lu J, Roberts A, Land CV, Muzumdar R, Gong Z, Vockley J, Prochownik EV. Wang H, et al. bioRxiv [Preprint]. 2023 Nov 27:2023.11.26.568749. doi: 10.1101/2023.11.26.568749. bioRxiv. 2023. PMID: 38076995 Free PMC article. Preprint.

3

Normal and Neoplastic Growth Suppression by the Extended Myc Network.

Prochownik EV, Wang H. Prochownik EV, et al. Among authors: wang h. Cells. 2022 Feb 21;11(4):747. doi: 10.3390/cells11040747. Cells. 2022. PMID: 35203395 Free PMC article. Review.

4

Lessons in aging from Myc knockout mouse models.

Prochownik EV, Wang H. Prochownik EV, et al. Among authors: wang h. Front Cell Dev Biol. 2023 Aug 9;11:1244321. doi: 10.3389/fcell.2023.1244321. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37621775 Free PMC article. Review.

5

Body-Wide Inactivation of the Myc-Like Mlx Transcription Factor Network Accelerates Aging and Increases the Lifetime Cancer Incidence.

Wang H, Stevens T, Lu J, Roberts A, Van't Land C, Muzumdar R, Gong Z, Vockley J, Prochownik EV. Wang H, et al. Adv Sci (Weinh). 2024 Sep;11(34):e2401593. doi: 10.1002/advs.202401593. Epub 2024 Jul 8. Adv Sci (Weinh). 2024. PMID: 38976573 Free PMC article.

6

Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules.

Follis AV, Hammoudeh DI, Wang H, Prochownik EV, Metallo SJ. Follis AV, et al. Among authors: wang h. Chem Biol. 2008 Nov 24;15(11):1149-55. doi: 10.1016/j.chembiol.2008.09.011. Chem Biol. 2008. PMID: 19022175

7

Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice.

Wang H, Dolezal JM, Kulkarni S, Lu J, Mandel J, Jackson LE, Alencastro F, Duncan AW, Prochownik EV. Wang H, et al. J Biol Chem. 2018 Sep 21;293(38):14740-14757. doi: 10.1074/jbc.RA118.004099. Epub 2018 Aug 7. J Biol Chem. 2018. PMID: 30087120 Free PMC article.

8

Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation.

Wang H, Lu J, Stevens T, Roberts A, Mandel J, Avula R, Ma B, Wu Y, Wang J, Land CV, Finkel T, Vockley JE, Airik M, Airik R, Muzumdar R, Gong Z, Torbenson MS, Prochownik EV. Wang H, et al. Among authors: wang j. Cell Rep. 2023 Aug 29;42(8):112830. doi: 10.1016/j.celrep.2023.112830. Epub 2023 Jul 22. Cell Rep. 2023. PMID: 37481724 Free PMC article.

9

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion.

Wang H, Sharma L, Lu J, Finch P, Fletcher S, Prochownik EV. Wang H, et al. Oncotarget. 2015 Jun 30;6(18):15857-70. doi: 10.18632/oncotarget.4327. Oncotarget. 2015. PMID: 26036281 Free PMC article.

10

A quantitative, surface plasmon resonance-based approach to evaluating DNA binding by the c-Myc oncoprotein and its disruption by small molecule inhibitors.

Wang H, Ramakrishnan A, Fletcher S, Prochownik EV. Wang H, et al. J Biol Methods. 2015;2(2):e18. doi: 10.14440/jbm.2015.54. J Biol Methods. 2015. PMID: 26280010 Free PMC article.

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