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Page 1
Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines.
Fantin RF, Clark JJ, Cohn H, Jaiswal D, Bozarth B, Civljak A, Rao V, Lobo I, Nardulli JR, Srivastava K, Yong J, Andreata-Santos R, Bushfield K, Lee ES, Singh G; PVI Study Group; Kleinstein SH, Krammer F, Simon V, Bajic G, Coelho CH. Fantin RF, et al. Among authors: simon v. bioRxiv [Preprint]. 2024 Jul 16:2024.07.15.602781. doi: 10.1101/2024.07.15.602781. bioRxiv. 2024. PMID: 39071292 Free PMC article. Preprint.
Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination.
Clark J, Hoxie I, Adelsberg DC, Sapse IA, Andreata-Santos R, Yong JS, Amanat F, Tcheou J, Raskin A, Singh G, González-Domínguez I, Edgar JE, Bournazos S, Sun W, Carreño JM, Simon V, Ellebedy AH, Bajic G, Krammer F. Clark J, et al. Among authors: simon v. bioRxiv [Preprint]. 2024 Mar 1:2024.02.28.582613. doi: 10.1101/2024.02.28.582613. bioRxiv. 2024. Update in: Cell Rep. 2024 Nov 26;43(11):114922. doi: 10.1016/j.celrep.2024.114922 PMID: 38464151 Free PMC article. Updated. Preprint.
T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Bozkus CC, Brown M, Velazquez L, Thomas M, Wilson EA, O'Donnell T, Ruchnewitz D, Geertz D, Bykov Y, Kodysh J, Oguntuyo KY, Roudko V, Hoyos D, Srivastava KD, Kleiner G, Alshammary H, Karekar N, McClain C, Gopal R, Nie K, Del Valle D, Delbeau-Zagelbaum D, Rodriguez D, Setal J; Mount Sinai COVID-19 Biobank Team; Carroll E, Wiesendanger M, Gulko PS, Charney A, Merad M, Kim-Schulze S, Lee B, Wajnberg A, Simon V, Greenbaum BD, Chowell D, Vabret N, Luksza M, Bhardwaj N. Bozkus CC, et al. Among authors: simon v. bioRxiv [Preprint]. 2024 Oct 24:2024.10.23.619918. doi: 10.1101/2024.10.23.619918. bioRxiv. 2024. PMID: 39484455 Free PMC article. Preprint.
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH; IMPACC Network; Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E. Maguire C, et al. Among authors: simon v. bioRxiv [Preprint]. 2024 Nov 16:2024.11.14.622799. doi: 10.1101/2024.11.14.622799. bioRxiv. 2024. PMID: 39605478 Free PMC article. Preprint.
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping.
Wang K, Nie Y, Maguire C, Syphurs C, Sheen H, Karoly M, Lapp L, Gygi JP, Jayavelu ND, Patel RK, Hoch A; IMPACC Network; Corry D, Kheradmand F, McComsey GA, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, Davis MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Hafler DA, Shaw A, Rahman A, Hough CL, Geng LN, Ozonoff A, Haddad EK, Reed EF, van Bakel H, Kim-Schultz S, Krammer F, Wilson M, Eckalbar W, Bosinger S, Langelier CR, Sekaly RP, Montgomery RR, Maecker HT, Krumholz H, Melamed E, Steen H, Pulendran B, Augustine AD, Cairns CB, Rouphael N, Becker PM, Fourati S, Shannon CP, Smolen KK, Peters B, Kleinstein SH, Levy O, Altman MC, Iwasaki A, Diray-Arce J, Ehrlich LIR, Guan L. Wang K, et al. Among authors: simon v. bioRxiv [Preprint]. 2024 Nov 25:2024.11.22.624784. doi: 10.1101/2024.11.22.624784. bioRxiv. 2024. PMID: 39651165 Free PMC article. Preprint.
The immunodominance of antigenic site Sb on the H1 influenza virus hemagglutinin increases with high immunoglobulin titers of the cohorts and with young age, but not sex.
Martínez JL, Lemus N, Lai TY, Mishra M, González-Domínguez I, Puente-Massaguer E, Loganathan M, Francis B, Samanovic MI, Krammer F, Mulligan MJ, Simon V, Palese P, Sun W. Martínez JL, et al. Among authors: simon v. Vaccine. 2024 May 22;42(14):3365-3373. doi: 10.1016/j.vaccine.2024.04.037. Epub 2024 Apr 15. Vaccine. 2024. PMID: 38627145 Free article.
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W; IMPACC Network; Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR. Pickering H, et al. Nat Commun. 2025 Jan 10;16(1):586. doi: 10.1038/s41467-025-55823-z. Nat Commun. 2025. PMID: 39794319 Free PMC article.
A surrogate ELISA to select high titer human convalescent plasma for treating immunocompromised patients infected with SARS-CoV-2 variants of concern.
Dolange V, Slamanig S, Abdeljawad A, Ying TL, Lemus N, Singh G, Carreño JM, Abad A, Srivastava K, Simon V, Sachithanandham J, Pekosz A, Sullivan D, Krammer F, Sun W, Palese P, González-Domínguez I. Dolange V, et al. Among authors: simon v. J Infect Dis. 2025 Jan 3:jiae645. doi: 10.1093/infdis/jiae645. Online ahead of print. J Infect Dis. 2025. PMID: 39749487
Historical and Archaeogenomic Identification of High-Status Englishmen at Jamestown, Virginia.
Owsley DW, Bruwelheide KS, Harney É, Mallick S, Rohland N, Olalde I, Barca KG, Ramsey AJ, Hull-Walski DA, Kelso WM, May JE, Broomandkhoshbacht N, Ferry M, Lawson AM, Michel M, Oppenheimer J, Stewardson K, Zalzala F, Simon VE, Givens DM, Lavin MD, Reich DE. Owsley DW, et al. Among authors: simon ve. Antiquity. 2024 Aug;98(400):1040-1054. doi: 10.15184/aqy.2024.75. Epub 2024 Aug 13. Antiquity. 2024. PMID: 39697469 Free PMC article.
730 results