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Iron Chelation Therapy Elicits Innate Immune Control of Metastatic Ovarian Cancer.
Sandoval TA, Salvagno C, Chae CS, Awasthi D, Giovanelli P, Marin Falco M, Hwang SM, Teran-Cabanillas E, Suominen L, Yamazaki T, Kuo HH, Moyer JE, Martin ML, Manohar J, Kim K, Sierra MA, Ramos Y, Tan C, Emmanuelli A, Song M, Morales DK, Zamarin D, Frey MK, Cantillo E, Chapman-Davis E, Holcomb K, Mason CE, Galluzzi L, Ni Zhou Z, Vähärautio A, Cloonan SM, Cubillos-Ruiz JR. Sandoval TA, et al. Among authors: song m. Cancer Discov. 2024 Oct 4;14(10):1901-1921. doi: 10.1158/2159-8290.CD-23-1451. Cancer Discov. 2024. PMID: 39073085
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.
Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. Cubillos-Ruiz JR, et al. Among authors: song m. Cell. 2015 Jun 18;161(7):1527-38. doi: 10.1016/j.cell.2015.05.025. Epub 2015 Jun 11. Cell. 2015. PMID: 26073941 Free PMC article.
IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, Motorykin I, Zhang S, Manfredi G, Zamarin D, Holcomb K, Rodriguez PC, Rabinovich GA, Conejo-Garcia JR, Glimcher LH, Cubillos-Ruiz JR. Song M, et al. Nature. 2018 Oct;562(7727):423-428. doi: 10.1038/s41586-018-0597-x. Epub 2018 Oct 10. Nature. 2018. PMID: 30305738 Free PMC article.
IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.
Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR. Chopra S, et al. Among authors: song m. Science. 2019 Jul 19;365(6450):eaau6499. doi: 10.1126/science.aau6499. Science. 2019. PMID: 31320508
Tumor-Derived Lysophosphatidic Acid Blunts Protective Type I Interferon Responses in Ovarian Cancer.
Chae CS, Sandoval TA, Hwang SM, Park ES, Giovanelli P, Awasthi D, Salvagno C, Emmanuelli A, Tan C, Chaudhary V, Casado J, Kossenkov AV, Song M, Barrat FJ, Holcomb K, Romero-Sandoval EA, Zamarin D, Pépin D, D'Andrea AD, Färkkilä A, Cubillos-Ruiz JR. Chae CS, et al. Among authors: song m. Cancer Discov. 2022 Aug 5;12(8):1904-1921. doi: 10.1158/2159-8290.CD-21-1181. Cancer Discov. 2022. PMID: 35552618 Free PMC article.
Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function.
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Falco MM, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, Morales DK, Rodriguez PC, Conejo-Garcia JR, Kaczocha M, Vähärautio A, Song M, Cubillos-Ruiz JR. Hwang SM, et al. Among authors: song m. Res Sq [Preprint]. 2023 Dec 14:rs.3.rs-3683989. doi: 10.21203/rs.3.rs-3683989/v1. Res Sq. 2023. Update in: Nature. 2024 Nov;635(8040):1010-1018. doi: 10.1038/s41586-024-08071-y PMID: 38168227 Free PMC article. Updated. Preprint.
Transgelin 2 guards T cell lipid metabolism and antitumour function.
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Marin Falco M, Salvagno C, Emmanuelli A, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, Morales DK, Yu X, Rodriguez PC, Conejo-Garcia JR, Kaczocha M, Vähärautio A, Song M, Cubillos-Ruiz JR. Hwang SM, et al. Among authors: song m. Nature. 2024 Nov;635(8040):1010-1018. doi: 10.1038/s41586-024-08071-y. Epub 2024 Oct 23. Nature. 2024. PMID: 39443795
IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.
Adoro S, Cubillos-Ruiz JR, Chen X, Deruaz M, Vrbanac VD, Song M, Park S, Murooka TT, Dudek TE, Luster AD, Tager AM, Streeck H, Bowman B, Walker BD, Kwon DS, Lazarevic V, Glimcher LH. Adoro S, et al. Among authors: song m. Nat Commun. 2015 Jun 25;6:7562. doi: 10.1038/ncomms8562. Nat Commun. 2015. PMID: 26108174 Free PMC article.
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