Dickenson NE - Search Results

1

Structural and functional characterization of the IpaD π-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence.

Barker SA, Bernard AR, Morales Y, Johnson SJ, Dickenson NE. Barker SA, et al. Among authors: dickenson ne. J Biol Chem. 2024 Sep;300(9):107613. doi: 10.1016/j.jbc.2024.107613. Epub 2024 Jul 28. J Biol Chem. 2024. PMID: 39079629 Free PMC article.

2

Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation.

Burgess JL, Burgess RA, Morales Y, Bouvang JM, Johnson SJ, Dickenson NE. Burgess JL, et al. Among authors: dickenson ne. J Biol Chem. 2016 Dec 9;291(50):25837-25852. doi: 10.1074/jbc.M116.755256. Epub 2016 Oct 21. J Biol Chem. 2016. PMID: 27770024 Free PMC article.

3

Detergent Isolation Stabilizes and Activates the Shigella Type III Secretion System Translocator Protein IpaC.

Bernard AR, Duarte SM, Kumar P, Dickenson NE. Bernard AR, et al. Among authors: dickenson ne. J Pharm Sci. 2016 Jul;105(7):2240-8. doi: 10.1016/j.xphs.2016.05.015. Epub 2016 Jun 11. J Pharm Sci. 2016. PMID: 27297397 Free PMC article.

4

Deoxycholate-Enhanced Shigella Virulence Is Regulated by a Rare π-Helix in the Type Three Secretion System Tip Protein IpaD.

Bernard AR, Jessop TC, Kumar P, Dickenson NE. Bernard AR, et al. Among authors: dickenson ne. Biochemistry. 2017 Dec 12;56(49):6503-6514. doi: 10.1021/acs.biochem.7b00836. Epub 2017 Nov 22. Biochemistry. 2017. PMID: 29134812 Free PMC article.

5

Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.

Demler HJ, Case HB, Morales Y, Bernard AR, Johnson SJ, Dickenson NE. Demler HJ, et al. Among authors: dickenson ne. Proteins. 2019 Nov;87(11):931-942. doi: 10.1002/prot.25754. Epub 2019 Jun 21. Proteins. 2019. PMID: 31162724 Free PMC article.

6

Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence.

Burgess JL, Case HB, Burgess RA, Dickenson NE. Burgess JL, et al. Among authors: dickenson ne. PLoS One. 2020 Jan 24;15(1):e0228227. doi: 10.1371/journal.pone.0228227. eCollection 2020. PLoS One. 2020. PMID: 31978132 Free PMC article.

7

Phosphomimetic Tyrosine Mutations in Spa47 Inhibit Type Three Secretion ATPase Activity and Shigella Virulence Phenotype.

Hardy KD, Dickenson NE. Hardy KD, et al. Among authors: dickenson ne. Pathogens. 2022 Feb 3;11(2):202. doi: 10.3390/pathogens11020202. Pathogens. 2022. PMID: 35215145 Free PMC article.

8

N-terminus of IpaB provides a potential anchor to the Shigella type III secretion system tip complex protein IpaD.

Dickenson NE, Arizmendi O, Patil MK, Toth RT 4th, Middaugh CR, Picking WD, Picking WL. Dickenson NE, et al. Biochemistry. 2013 Dec 10;52(49):8790-9. doi: 10.1021/bi400755f. Epub 2013 Nov 20. Biochemistry. 2013. PMID: 24236510 Free PMC article.

9

Differential regulation of Shigella Spa47 ATPase activity by a native C-terminal product of Spa33.

Case HB, Gonzalez S, Gustafson ME, Dickenson NE. Case HB, et al. Among authors: dickenson ne. Front Cell Infect Microbiol. 2023 Jun 14;13:1183211. doi: 10.3389/fcimb.2023.1183211. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37389216 Free PMC article.

10

Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase from Shigella flexneri.

Burgess JL, Jones HB, Kumar P, Toth RT 4th, Middaugh CR, Antony E, Dickenson NE. Burgess JL, et al. Among authors: dickenson ne. Protein Sci. 2016 May;25(5):1037-48. doi: 10.1002/pro.2917. Epub 2016 Mar 22. Protein Sci. 2016. PMID: 26947936 Free PMC article.

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