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Page 1
Calcium has a direct effect on thick filament activation in porcine myocardium.
Mohran S, McMillen TS, Mandrycky C, Tu AY, Kooiker KB, Qian W, Neys S, Osegueda B, Moussavi-Harami F, Irving TC, Regnier M, Ma W. Mohran S, et al. Among authors: kooiker kb. J Gen Physiol. 2024 Nov 4;156(11):e202413545. doi: 10.1085/jgp.202413545. Epub 2024 Sep 20. J Gen Physiol. 2024. PMID: 39302315
Mechanisms of a novel regulatory light chain-dependent cardiac myosin inhibitor.
Kooiker K, Gan QF, Yu M, Sa N, Mohran S, Cheng Y, Flint G, Neys S, Gao C, Nissen D, McMillen T, Asencio A, Ma W, Irving TC, Moussavi-Harami F, Regnier M. Kooiker K, et al. J Gen Physiol. 2024 Oct 7;156(10):e202313503. doi: 10.1085/jgp.202313503. Epub 2024 Jul 31. J Gen Physiol. 2024. PMID: 39083045
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
Steczina S, Mohran S, Bailey LRJ, McMillen TS, Kooiker KB, Wood NB, Davis J, Previs MJ, Olivotto I, Pioner JM, Geeves MA, Poggesi C, Regnier M. Steczina S, et al. Among authors: kooiker kb. J Mol Cell Cardiol. 2024 Jun;191:27-39. doi: 10.1016/j.yjmcc.2024.04.010. Epub 2024 Apr 20. J Mol Cell Cardiol. 2024. PMID: 38648963
The biochemically defined super relaxed state of myosin-A paradox.
Mohran S, Kooiker K, Mahoney-Schaefer M, Mandrycky C, Kao K, Tu AY, Freeman J, Moussavi-Harami F, Geeves M, Regnier M. Mohran S, et al. Among authors: kooiker k. J Biol Chem. 2024 Jan;300(1):105565. doi: 10.1016/j.jbc.2023.105565. Epub 2023 Dec 14. J Biol Chem. 2024. PMID: 38103642 Free PMC article.
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.
Kooiker KB, Mohran S, Turner KL, Ma W, Martinson A, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, Irving TC, Geeves MA, Tanner BCW, Regnier M, Davis J, Moussavi-Harami F. Kooiker KB, et al. Circ Res. 2023 Aug 18;133(5):430-443. doi: 10.1161/CIRCRESAHA.123.322629. Epub 2023 Jul 20. Circ Res. 2023. PMID: 37470183 Free PMC article.
25 results