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Structures of TGF-β with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling.
Wieteska Ł, Taylor AB, Punch E, Coleman JA, Conway IO, Lin YF, Byeon CH, Hinck CS, Krzysiak T, Ishima R, López-Casillas F, Cherepanov P, Bernard DJ, Hill CS, Hinck AP. Wieteska Ł, et al. Among authors: lin yf. bioRxiv [Preprint]. 2024 Jul 22:2024.07.19.604101. doi: 10.1101/2024.07.19.604101. bioRxiv. 2024. PMID: 39091787 Free PMC article. Preprint.
TGFBR3L is an inhibin B co-receptor that regulates female fertility.
Brûlé E, Wang Y, Li Y, Lin YF, Zhou X, Ongaro L, Alonso CAI, Buddle ERS, Schneyer AL, Byeon CH, Hinck CS, Mendelev N, Russell JP, Cowan M, Boehm U, Ruf-Zamojski F, Zamojski M, Andoniadou CL, Sealfon SC, Harrison CA, Walton KL, Hinck AP, Bernard DJ. Brûlé E, et al. Among authors: lin yf. Sci Adv. 2021 Dec 17;7(51):eabl4391. doi: 10.1126/sciadv.abl4391. Epub 2021 Dec 15. Sci Adv. 2021. PMID: 34910520 Free PMC article.
Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice.
Toufaily C, Fortin J, Alonso CA, Lapointe E, Zhou X, Santiago-Andres Y, Lin YF, Cui Y, Wang Y, Devost D, Roelfsema F, Steyn F, Hanyaloglu AC, Hébert TE, Fiordelisio T, Boerboom D, Bernard DJ. Toufaily C, et al. Among authors: lin yf. Elife. 2021 Dec 23;10:e72937. doi: 10.7554/eLife.72937. Elife. 2021. PMID: 34939930 Free PMC article.
1,232 results