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Page 1
An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia.
Torres-Diz M, Reglero C, Falkenstein CD, Castro A, Hayer KE, Radens CM, Quesnel-Vallières M, Ang Z, Sehgal P, Li MM, Barash Y, Tasian SK, Ferrando A, Thomas-Tikhonenko A. Torres-Diz M, et al. Among authors: thomas tikhonenko a. Cancer Res. 2024 Oct 15;84(20):3327-3336. doi: 10.1158/0008-5472.CAN-23-3804. Cancer Res. 2024. PMID: 39094066 Free PMC article.
Infection and cancer: the common vein.
Thomas-Tikhonenko A, Hunter CA. Thomas-Tikhonenko A, et al. Cytokine Growth Factor Rev. 2003 Feb;14(1):67-77. doi: 10.1016/s1359-6101(02)00071-0. Cytokine Growth Factor Rev. 2003. PMID: 12485620 Review.
Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.
Sotillo E, Barrett DM, Black KL, Bagashev A, Oldridge D, Wu G, Sussman R, Lanauze C, Ruella M, Gazzara MR, Martinez NM, Harrington CT, Chung EY, Perazzelli J, Hofmann TJ, Maude SL, Raman P, Barrera A, Gill S, Lacey SF, Melenhorst JJ, Allman D, Jacoby E, Fry T, Mackall C, Barash Y, Lynch KW, Maris JM, Grupp SA, Thomas-Tikhonenko A. Sotillo E, et al. Cancer Discov. 2015 Dec;5(12):1282-95. doi: 10.1158/2159-8290.CD-15-1020. Epub 2015 Oct 29. Cancer Discov. 2015. PMID: 26516065 Free PMC article.
Aberrant splicing in B-cell acute lymphoblastic leukemia.
Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A. Black KL, et al. Nucleic Acids Res. 2018 Nov 30;46(21):11357-11369. doi: 10.1093/nar/gky946. Nucleic Acids Res. 2018. PMID: 30357359 Free PMC article.
Aberrant splicing in B-cell acute lymphoblastic leukemia.
Black KL, Naqvi AS, Asnani M, Hayer KE, Yang SY, Gillespie E, Bagashev A, Pillai V, Tasian SK, Gazzara MR, Carroll M, Taylor D, Lynch KW, Barash Y, Thomas-Tikhonenko A. Black KL, et al. Nucleic Acids Res. 2019 Jan 25;47(2):1043. doi: 10.1093/nar/gky1231. Nucleic Acids Res. 2019. PMID: 30517739 Free PMC article. No abstract available.
Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.
Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Harrington CT, et al. Leukemia. 2019 Oct;33(10):2429-2441. doi: 10.1038/s41375-019-0454-4. Epub 2019 Mar 26. Leukemia. 2019. PMID: 30914792 Free PMC article.
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19.
Asnani M, Hayer KE, Naqvi AS, Zheng S, Yang SY, Oldridge D, Ibrahim F, Maragkakis M, Gazzara MR, Black KL, Bagashev A, Taylor D, Mourelatos Z, Grupp SA, Barrett D, Maris JM, Sotillo E, Barash Y, Thomas-Tikhonenko A. Asnani M, et al. Leukemia. 2020 Apr;34(4):1202-1207. doi: 10.1038/s41375-019-0580-z. Epub 2019 Oct 7. Leukemia. 2020. PMID: 31591467 Free PMC article. No abstract available.
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