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Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma.
Howell I, Yang F, Brown V, Cane J, Marchi E, Azim A, Busby J, McDowell PJ, Diver SE, Borg C, Heaney LG, Pavord ID, Brightling CE, Chaudhuri R, Hinks TSC. Howell I, et al. Among authors: borg c. J Allergy Clin Immunol. 2024 Aug 2:S0091-6749(24)00777-2. doi: 10.1016/j.jaci.2024.07.020. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39097197 Free article.
Relationship between inflammatory status and microbial composition in severe asthma and during exacerbation.
Diver S, Haldar K, McDowell PJ, Busby J, Mistry V, Micieli C, Brown V, Cox C, Yang F, Borg C, Shrimanker R, Ramsheh MY, Hardman T, Arron J, Bradding P, Cowan D, Mansur AH, Fowler SJ, Lordan J, Menzies-Gow A, Robinson D, Matthews J, Pavord ID, Chaudhuri R, Heaney LG, Barer MR, Brightling C; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). Diver S, et al. Among authors: borg c. Allergy. 2022 Nov;77(11):3362-3376. doi: 10.1111/all.15425. Epub 2022 Jul 15. Allergy. 2022. PMID: 35778780 Free article.
Synergistic activation of pro-inflammatory type-2 CD8+ T lymphocytes by lipid mediators in severe eosinophilic asthma.
Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L. Hilvering B, et al. Among authors: borg c. Mucosal Immunol. 2018 Sep;11(5):1408-1419. doi: 10.1038/s41385-018-0049-9. Epub 2018 Jun 15. Mucosal Immunol. 2018. PMID: 29907870 Free PMC article.
The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study.
McDowell PJ, Diver S, Yang F, Borg C, Busby J, Brown V, Shrimanker R, Cox C, Brightling CE, Chaudhuri R, Pavord ID, Heaney LG; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). McDowell PJ, et al. Among authors: borg c. Lancet Respir Med. 2021 Oct;9(10):1174-1184. doi: 10.1016/S2213-2600(21)00004-7. Epub 2021 May 7. Lancet Respir Med. 2021. PMID: 33971168
Correction: Synergistic activation of pro-inflammatory type-2 CD8 + T lymphocytes by lipid mediators in severe eosinophilic asthma.
Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L. Hilvering B, et al. Among authors: borg c. Mucosal Immunol. 2019 Mar;12(2):581. doi: 10.1038/s41385-018-0121-5. Mucosal Immunol. 2019. PMID: 30518781 Free PMC article.
Composite type-2 biomarker strategy versus a symptom-risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial.
Heaney LG, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker SM, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Mansur AH, Fowler SJ, Niven RM, Howarth PH, Lordan JL, Menzies-Gow A, Harrison TW, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID; investigators for the MRC Refractory Asthma Stratification Programme. Heaney LG, et al. Lancet Respir Med. 2021 Jan;9(1):57-68. doi: 10.1016/S2213-2600(20)30397-0. Epub 2020 Sep 8. Lancet Respir Med. 2021. PMID: 32916135 Free PMC article. Clinical Trial.
Asthma in pregnancy: An update.
Couillard S, Connolly C, Borg C, Pavord I. Couillard S, et al. Among authors: borg c. Obstet Med. 2021 Sep;14(3):135-144. doi: 10.1177/1753495X20965072. Epub 2020 Nov 1. Obstet Med. 2021. PMID: 34646341 Free PMC article. Review.
471 results