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Discovery of gem-Dimethyl-hydroxymethylpyridine Derivatives as Potent Non-nucleoside RSV Polymerase Inhibitors.
Grosse S, Cooymans L, Embrechts W, McGowan D, Jacoby E, Stoops B, Gupta K, Ackermann M, Alnajjar S, Guillemont J, Jin Z, Kesteleyn B, Matcha K, Sriboonyapirat P, Truong A, Van Den Berg J, Yu X, Herschke F, Roymans D, Raboisson P, Rigaux P, Jonckers THM. Grosse S, et al. Among authors: yu x. J Med Chem. 2024 Aug 22;67(16):13723-13736. doi: 10.1021/acs.jmedchem.4c00525. Epub 2024 Aug 6. J Med Chem. 2024. PMID: 39105710
Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
Tran MT, Grosse S, Carbajo RJ, Jacoby E, Yin Y, Yu X, Martinez C, Stoops B, Cooymans L, Hu L, Lutter FH, Pieters S, Tan E, Alcázar J, Roymans D, van Vlijmen H, Rigaux P, Sharma S, Jonckers THM. Tran MT, et al. Among authors: yu x. ACS Med Chem Lett. 2024 Aug 2;15(9):1549-1558. doi: 10.1021/acsmedchemlett.4c00272. eCollection 2024 Sep 12. ACS Med Chem Lett. 2024. PMID: 39291020
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