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Page 1
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks.
Cassandri M, Porrazzo A, Pomella S, Noce B, Zwergel C, Aiello FA, Vulcano F, Milazzo L, Camero S, Pajalunga D, Spada M, Manzi V, Gravina GL, Codenotti S, Piccione M, Tomaciello M, Signore M, Barillari G, Marchese C, Fanzani A, De Angelis B, Quintarelli C, Vakoc CR, Chen EY, Megiorni F, Locatelli F, Valente S, Mai A, Rota R, Marampon F. Cassandri M, et al. Among authors: noce b. Cell Death Discov. 2024 Aug 6;10(1):351. doi: 10.1038/s41420-024-02115-y. Cell Death Discov. 2024. PMID: 39107280 Free PMC article.
Targeting ROS production through inhibition of NADPH oxidases.
Reis J, Gorgulla C, Massari M, Marchese S, Valente S, Noce B, Basile L, Törner R, Cox H 3rd, Viennet T, Yang MH, Ronan MM, Rees MG, Roth JA, Capasso L, Nebbioso A, Altucci L, Mai A, Arthanari H, Mattevi A. Reis J, et al. Among authors: noce b. Nat Chem Biol. 2023 Dec;19(12):1540-1550. doi: 10.1038/s41589-023-01457-5. Epub 2023 Oct 26. Nat Chem Biol. 2023. PMID: 37884805
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells.
Zwergel C, Aventaggiato M, Garbo S, Di Bello E, Fassari B, Noce B, Castiello C, Lambona C, Barreca F, Rotili D, Fioravanti R, Schmalz T, Weyand M, Niedermeier A, Tripodi M, Colotti G, Steegborn C, Battistelli C, Tafani M, Valente S, Mai A. Zwergel C, et al. Among authors: noce b. J Med Chem. 2023 Jul 27;66(14):9622-9641. doi: 10.1021/acs.jmedchem.3c00337. Epub 2023 Jul 13. J Med Chem. 2023. PMID: 37439550 Free PMC article.
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells.
Di Bello E, Sian V, Bontempi G, Zwergel C, Fioravanti R, Noce B, Castiello C, Tomassi S, Corinti D, Passeri D, Pellicciari R, Mercurio C, Varasi M, Altucci L, Tripodi M, Strippoli R, Nebbioso A, Valente S, Mai A. Di Bello E, et al. Among authors: noce b. Eur J Med Chem. 2023 Feb 5;247:115022. doi: 10.1016/j.ejmech.2022.115022. Epub 2022 Dec 15. Eur J Med Chem. 2023. PMID: 36549114
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni.
Di Bello E, Noce B, Fioravanti R, Zwergel C, Valente S, Rotili D, Fianco G, Trisciuoglio D, Mourão MM, Sales P Jr, Lamotte S, Prina E, Späth GF, Häberli C, Keiser J, Mai A. Di Bello E, et al. Among authors: noce b. ACS Infect Dis. 2022 Jul 8;8(7):1356-1366. doi: 10.1021/acsinfecdis.2c00232. Epub 2022 Jun 22. ACS Infect Dis. 2022. PMID: 35732073 Free PMC article.
Current HDAC Inhibitors in Clinical Trials.
Di Bello E, Noce B, Fioravanti R, Mai A. Di Bello E, et al. Among authors: noce b. Chimia (Aarau). 2022 May 25;76(5):448-453. doi: 10.2533/chimia.2022.448. Chimia (Aarau). 2022. PMID: 38069716 Free article.
Correction: Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line.
Della Noce B, Martins da Silva R, Vianna de Carvalho Uhl M, Konnai S, Ohashi K, Calixto C, Arcanjo A, Araujo de Abreu L, Serafim de Carvalho S, da Silva Vaz I Jr, Logullo C. Della Noce B, et al. J Biol Chem. 2022 Apr;298(4):101878. doi: 10.1016/j.jbc.2022.101878. Epub 2022 Apr 8. J Biol Chem. 2022. PMID: 35405592 Free PMC article. No abstract available.
15 results