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HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks.
Cassandri M, Porrazzo A, Pomella S, Noce B, Zwergel C, Aiello FA, Vulcano F, Milazzo L, Camero S, Pajalunga D, Spada M, Manzi V, Gravina GL, Codenotti S, Piccione M, Tomaciello M, Signore M, Barillari G, Marchese C, Fanzani A, De Angelis B, Quintarelli C, Vakoc CR, Chen EY, Megiorni F, Locatelli F, Valente S, Mai A, Rota R, Marampon F. Cassandri M, et al. Among authors: rota r. Cell Death Discov. 2024 Aug 6;10(1):351. doi: 10.1038/s41420-024-02115-y. Cell Death Discov. 2024. PMID: 39107280 Free PMC article.
The CRISP(Y) Future of Pediatric Soft Tissue Sarcomas.
Pomella S, Rota R. Pomella S, et al. Among authors: rota r. Front Chem. 2020 Mar 13;8:178. doi: 10.3389/fchem.2020.00178. eCollection 2020. Front Chem. 2020. PMID: 32232030 Free PMC article. Review.
FAK Signaling in Rhabdomyosarcoma.
Perrone C, Pomella S, Cassandri M, Braghini MR, Pezzella M, Locatelli F, Rota R. Perrone C, et al. Among authors: rota r. Int J Mol Sci. 2020 Nov 10;21(22):8422. doi: 10.3390/ijms21228422. Int J Mol Sci. 2020. PMID: 33182556 Free PMC article. Review.
Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype.
Rossetti A, Petragnano F, Milazzo L, Vulcano F, Macioce G, Codenotti S, Cassandri M, Pomella S, Cicchetti F, Fasciani I, Antinozzi C, Di Luigi L, Festuccia C, De Felice F, Vergine M, Fanzani A, Rota R, Maggio R, Polimeni A, Tombolini V, Gravina GL, Marampon F. Rossetti A, et al. Among authors: rota r. Int J Radiat Biol. 2021;97(7):943-957. doi: 10.1080/09553002.2021.1928786. Epub 2021 Jun 4. Int J Radiat Biol. 2021. PMID: 33979259
MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.
Cassandri M, Pomella S, Rossetti A, Petragnano F, Milazzo L, Vulcano F, Camero S, Codenotti S, Cicchetti F, Maggio R, Festuccia C, Gravina GL, Fanzani A, Megiorni F, Catanoso M, Marchese C, Tombolini V, Locatelli F, Rota R, Marampon F. Cassandri M, et al. Among authors: rota r. Int J Mol Sci. 2021 Oct 1;22(19):10671. doi: 10.3390/ijms221910671. Int J Mol Sci. 2021. PMID: 34639012 Free PMC article.
MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression.
Perrone C, Pomella S, Cassandri M, Pezzella M, Milano GM, Colletti M, Cossetti C, Pericoli G, Di Giannatale A, de Billy E, Vinci M, Petrini S, Marampon F, Quintarelli C, Taulli R, Roma J, Gallego S, Camero S, Mariottini P, Cervelli M, Maestro R, Miele L, De Angelis B, Locatelli F, Rota R. Perrone C, et al. Among authors: rota r. Front Oncol. 2022 Apr 27;12:835642. doi: 10.3389/fonc.2022.835642. eCollection 2022. Front Oncol. 2022. PMID: 35574376 Free PMC article.
Radioresistance in rhabdomyosarcomas: Much more than a question of dose.
Camero S, Cassandri M, Pomella S, Milazzo L, Vulcano F, Porrazzo A, Barillari G, Marchese C, Codenotti S, Tomaciello M, Rota R, Fanzani A, Megiorni F, Marampon F. Camero S, et al. Among authors: rota r. Front Oncol. 2022 Sep 29;12:1016894. doi: 10.3389/fonc.2022.1016894. eCollection 2022. Front Oncol. 2022. PMID: 36248991 Free PMC article. Review.
Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma.
Pomella S, Porrazzo A, Cassandri M, Camero S, Codenotti S, Milazzo L, Vulcano F, Barillari G, Cenci G, Marchese C, Fanzani A, Megiorni F, Rota R, Marampon F. Pomella S, et al. Among authors: rota r. Int J Mol Sci. 2022 Oct 31;23(21):13281. doi: 10.3390/ijms232113281. Int J Mol Sci. 2022. PMID: 36362070 Free PMC article. Review.
The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo.
Vaccaro S, Rossetti A, Porrazzo A, Camero S, Cassandri M, Pomella S, Tomaciello M, Macioce G, Pedini F, Barillari G, Marchese C, Rota R, Cenci G, Tombolini M, Newman RA, Yang P, Codenotti S, Fanzani A, Megiorni F, Festuccia C, Minniti G, Gravina GL, Vulcano F, Milazzo L, Marampon F. Vaccaro S, et al. Among authors: rota r. Front Pharmacol. 2022 Dec 1;13:1071176. doi: 10.3389/fphar.2022.1071176. eCollection 2022. Front Pharmacol. 2022. PMID: 36532747 Free PMC article.
134 results