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Age-related epithelial defects limit thymic function and regeneration.
Kousa AI, Jahn L, Zhao K, Flores AE, Acenas D 2nd, Lederer E, Argyropoulos KV, Lemarquis AL, Granadier D, Cooper K, D'Andrea M, Sheridan JM, Tsai J, Sikkema L, Lazrak A, Nichols K, Lee N, Ghale R, Malard F, Andrlova H, Velardi E, Youssef S, Burgos da Silva M, Docampo M, Sharma R, Mazutis L, Wimmer VC, Rogers KL, DeWolf S, Gipson B, Gomes ALC, Setty M, Pe'er D, Hale L, Manley NR, Gray DHD, van den Brink MRM, Dudakov JA. Kousa AI, et al. Among authors: dudakov ja. Nat Immunol. 2024 Sep;25(9):1593-1606. doi: 10.1038/s41590-024-01915-9. Epub 2024 Aug 7. Nat Immunol. 2024. PMID: 39112630 Free PMC article.
Interleukin-22: immunobiology and pathology.
Dudakov JA, Hanash AM, van den Brink MR. Dudakov JA, et al. Annu Rev Immunol. 2015;33:747-85. doi: 10.1146/annurev-immunol-032414-112123. Epub 2015 Feb 11. Annu Rev Immunol. 2015. PMID: 25706098 Free PMC article. Review.
Thymus: the next (re)generation.
Chaudhry MS, Velardi E, Dudakov JA, van den Brink MR. Chaudhry MS, et al. Among authors: dudakov ja. Immunol Rev. 2016 May;271(1):56-71. doi: 10.1111/imr.12418. Immunol Rev. 2016. PMID: 27088907 Free PMC article. Review.
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.
Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM. Wertheimer T, et al. Among authors: dudakov ja. Sci Immunol. 2018 Jan 12;3(19):eaal2736. doi: 10.1126/sciimmunol.aal2736. Sci Immunol. 2018. PMID: 29330161 Free PMC article.
Supply-side economics finds the thymus.
Dudakov JA, Van den Brink MR. Dudakov JA, et al. Blood. 2011 Aug 18;118(7):1715-6. doi: 10.1182/blood-2011-06-361337. Blood. 2011. PMID: 21852443 Free article. No abstract available.
Interleukin-22 drives endogenous thymic regeneration in mice.
Dudakov JA, Hanash AM, Jenq RR, Young LF, Ghosh A, Singer NV, West ML, Smith OM, Holland AM, Tsai JJ, Boyd RL, van den Brink MR. Dudakov JA, et al. Science. 2012 Apr 6;336(6077):91-5. doi: 10.1126/science.1218004. Epub 2012 Mar 1. Science. 2012. PMID: 22383805 Free PMC article.
49 results