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T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study.
Gainor JF, Patel MR, Weber JS, Gutierrez M, Bauman JE, Clarke JM, Julian R, Scott AJ, Geiger JL, Kirtane K, Robert-Tissot C, Coder B, Tasneem M, Sun J, Zheng W, Gerbereux L, Laino A, Porichis F, Pollard JR, Hou P, Sehgal V, Chen X, Morrissey M, Daghestani HN, Feldman I, Srinivasan L, Frederick JP, Brown M, Aanur P, Meehan R, Burris HA 3rd. Gainor JF, et al. Among authors: daghestani hn. Cancer Discov. 2024 Nov 1;14(11):2209-2223. doi: 10.1158/2159-8290.CD-24-0158. Cancer Discov. 2024. PMID: 39115419 Clinical Trial.
Total Synthesis and Biological Evaluation of Tubulysin Analogues.
Colombo R, Wang Z, Han J, Balachandran R, Daghestani HN, Camarco DP, Vogt A, Day BW, Mendel D, Wipf P. Colombo R, et al. Among authors: daghestani hn. J Org Chem. 2016 Nov 4;81(21):10302-10320. doi: 10.1021/acs.joc.6b01314. Epub 2016 Aug 5. J Org Chem. 2016. PMID: 27447195
Inflammatory biomarkers in osteoarthritis.
Daghestani HN, Kraus VB. Daghestani HN, et al. Osteoarthritis Cartilage. 2015 Nov;23(11):1890-6. doi: 10.1016/j.joca.2015.02.009. Osteoarthritis Cartilage. 2015. PMID: 26521734 Free PMC article. Review.
N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. Salum LB, et al. Among authors: daghestani hn. Eur J Med Chem. 2015;96:504-18. doi: 10.1016/j.ejmech.2015.02.041. Epub 2015 Feb 23. Eur J Med Chem. 2015. PMID: 25951294
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.
Salum LB, Altei WF, Chiaradia LD, Cordeiro MN, Canevarolo RR, Melo CP, Winter E, Mattei B, Daghestani HN, Santos-Silva MC, Creczynski-Pasa TB, Yunes RA, Yunes JA, Andricopulo AD, Day BW, Nunes RJ, Vogt A. Salum LB, et al. Among authors: daghestani hn. Eur J Med Chem. 2013 May;63:501-10. doi: 10.1016/j.ejmech.2013.02.037. Epub 2013 Mar 6. Eur J Med Chem. 2013. PMID: 23524161 Free PMC article.
Ligand-induced architecture of the leptin receptor signaling complex.
Mancour LV, Daghestani HN, Dutta S, Westfield GH, Schilling J, Oleskie AN, Herbstman JF, Chou SZ, Skiniotis G. Mancour LV, et al. Among authors: daghestani hn. Mol Cell. 2012 Nov 30;48(4):655-61. doi: 10.1016/j.molcel.2012.09.003. Epub 2012 Oct 11. Mol Cell. 2012. PMID: 23063524 Free PMC article.
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