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The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia.
Milosavljević F, Brusini I, Atanasov A, Manojlović M, Vučić M, Oreščanin-Dušić Z, Brkljačić J, Miljević Č, Nikolić-Kokić A, Blagojević D, Wang C, Damberg P, Pešić V, Tyndale RF, Ingelman-Sundberg M, Jukić MM. Milosavljević F, et al. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12867. doi: 10.1111/nan.12867. Neuropathol Appl Neurobiol. 2023. PMID: 36536486 Free PMC article.
The Sixth European Society of Pharmacogenomics and Personalised Therapy Congress.
van Schaik RH, Manolopoulos VG, Daly AK, Niemi M, Zukic B, Patrinos GP, Primorac D, Swen JJ, Ingelman-Sundberg M, Morris T, Molden E, Müller D, Pavlovic S, Russmann S, Ansari M, Henricks LM, den Broek WV, Florindi F, Bozina N, Akin D, Christrup L, Llerena A, Sipeky C, Stankovic S. van Schaik RH, et al. Pharmacogenomics. 2023 Apr;24(5):243-246. doi: 10.2217/pgs-2023-0013. Epub 2023 Apr 4. Pharmacogenomics. 2023. PMID: 37014361
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study.
Swen JJ, van der Wouden CH, Manson LE, Abdullah-Koolmees H, Blagec K, Blagus T, Böhringer S, Cambon-Thomsen A, Cecchin E, Cheung KC, Deneer VH, Dupui M, Ingelman-Sundberg M, Jonsson S, Joefield-Roka C, Just KS, Karlsson MO, Konta L, Koopmann R, Kriek M, Lehr T, Mitropoulou C, Rial-Sebbag E, Rollinson V, Roncato R, Samwald M, Schaeffeler E, Skokou M, Schwab M, Steinberger D, Stingl JC, Tremmel R, Turner RM, van Rhenen MH, Dávila Fajardo CL, Dolžan V, Patrinos GP, Pirmohamed M, Sunder-Plassmann G, Toffoli G, Guchelaar HJ; Ubiquitous Pharmacogenomics Consortium. Swen JJ, et al. Lancet. 2023 Feb 4;401(10374):347-356. doi: 10.1016/S0140-6736(22)01841-4. Lancet. 2023. PMID: 36739136 Clinical Trial.
Rare variants and clozapine: Reply.
van Westrhenen R, Ingelman-Sundberg M. van Westrhenen R, et al. Among authors: ingelman sundberg m. Eur Neuropsychopharmacol. 2024 Jul;84:16-17. doi: 10.1016/j.euroneuro.2024.03.004. Epub 2024 Apr 20. Eur Neuropsychopharmacol. 2024. PMID: 38643694 No abstract available.
545 results