Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

15 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Elaborate Structural Modifications Yielding Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Potent Neuraminidase Inhibitors with Significantly Improved Broad-Spectrum Antiresistance Profiles.
Zhang J, Jia R, Jia H, Li P, Jiang Y, Bonomini A, Bertagnin C, Xu Q, Tan Z, Ma X, Loregian A, Huang B, Liu X, Zhan P. Zhang J, et al. Among authors: bonomini a. J Med Chem. 2024 Dec 26;67(24):22191-22217. doi: 10.1021/acs.jmedchem.4c02222. Epub 2024 Dec 7. J Med Chem. 2024. PMID: 39644238
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization.
Bonomini A, Felicetti T, Pacetti M, Bertagnin C, Coletti A, Giammarino F, De Angelis M, Poggialini F, Macchiarulo A, Sabatini S, Mercorelli B, Nencioni L, Vicenti I, Dreassi E, Cecchetti V, Tabarrini O, Loregian A, Massari S. Bonomini A, et al. Eur J Med Chem. 2024 Nov 5;277:116737. doi: 10.1016/j.ejmech.2024.116737. Epub 2024 Aug 3. Eur J Med Chem. 2024. PMID: 39153334
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines.
Pacetti M, Pismataro MC, Felicetti T, Giammarino F, Bonomini A, Tiecco M, Bertagnin C, Barreca ML, Germani R, Cecchetti V, Vicenti I, Tabarrini O, Zazzi M, Loregian A, Massari S. Pacetti M, et al. Among authors: bonomini a. Org Biomol Chem. 2024 Jan 24;22(4):767-783. doi: 10.1039/d3ob01861j. Org Biomol Chem. 2024. PMID: 38167738
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
Zhang J, Liu C, Jia R, Zhang X, Zhang J, Bertagnin C, Bonomini A, Guizzo L, Jiang Y, Jia H, Jia S, Ma X, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: bonomini a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2277135. doi: 10.1080/14756366.2023.2277135. Epub 2023 Nov 13. J Enzyme Inhib Med Chem. 2023. PMID: 37955306 Free PMC article.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Jia R, Zhang J, Shi F, Bonomini A, Lucca C, Bertagnin C, Zhang J, Liu C, Jia H, Jiang Y, Ma X, Loregian A, Huang B, Zhan P, Liu X. Jia R, et al. Among authors: bonomini a. Eur J Med Chem. 2023 Apr 5;252:115275. doi: 10.1016/j.ejmech.2023.115275. Epub 2023 Mar 13. Eur J Med Chem. 2023. PMID: 36931117
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity.
Ju H, Hou L, Zhao F, Zhang Y, Jia R, Guizzo L, Bonomini A, Zhang J, Gao Z, Liang R, Bertagnin C, Kong X, Ma X, Kang D, Loregian A, Huang B, Liu X, Zhan P. Ju H, et al. Among authors: bonomini a. J Med Chem. 2022 Sep 8;65(17):11550-11573. doi: 10.1021/acs.jmedchem.1c01970. Epub 2022 Aug 8. J Med Chem. 2022. PMID: 35939763
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors.
Pismataro MC, Felicetti T, Bertagnin C, Nizi MG, Bonomini A, Barreca ML, Cecchetti V, Jochmans D, De Jonghe S, Neyts J, Loregian A, Tabarrini O, Massari S. Pismataro MC, et al. Among authors: bonomini a. Eur J Med Chem. 2021 Oct 5;221:113494. doi: 10.1016/j.ejmech.2021.113494. Epub 2021 Apr 26. Eur J Med Chem. 2021. PMID: 33962311
15 results