Smith BJ - Search Results

1

Lenacapavir Exhibits Atropisomerism-Mechanistic Pharmacokinetics and Disposition Studies of Lenacapavir Reveal Intestinal Excretion as a Major Clearance Pathway.

Zheng J, Lu B, Carr G, Mwangi J, Wang K, Hao J, Staiger KM, Kozon N, Murray BP, Bashir M, Gohdes MA, Tse WC, Schroeder S, Graupe M, Link JO, Yoon J, Chiu A, Rowe W, Smith BJ, Subramanian R. Zheng J, et al. Among authors: smith bj. J Pharmacol Exp Ther. 2024 Sep 18;391(1):91-103. doi: 10.1124/jpet.124.002302. J Pharmacol Exp Ther. 2024. PMID: 39117460

2

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA. Zheng J, et al. Among authors: smith bj. Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8. Drug Metab Dispos. 2018. PMID: 29311136

3

Characterization of Seasonal Pharmacokinetic Variability in Woodchucks.

Zheng J, Balsitis S, Santos R, Smith BJ, Subramanian R. Zheng J, et al. Among authors: smith bj. Drug Metab Dispos. 2020 Nov;48(11):1199-1209. doi: 10.1124/dmd.120.000140. Epub 2020 Sep 5. Drug Metab Dispos. 2020. PMID: 32892154

4

¹⁸O-Enabled High-Throughput Acyl Glucuronide Stability Assay.

Yu ZJ, Le H, Tang J, Yue Q, Zhang J, Murray B, Liu X, Smith BJ, Subramanian R. Yu ZJ, et al. Among authors: smith bj. Chem Res Toxicol. 2022 Aug 15;35(8):1400-1409. doi: 10.1021/acs.chemrestox.2c00156. Epub 2022 Jul 14. Chem Res Toxicol. 2022. PMID: 35833852

5

Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.

Niu C, Wang Y, Zhao X, Tep S, Murakami E, Subramanian R, Smith B, Lai Y. Niu C, et al. Drug Metab Dispos. 2019 Dec;47(12):1433-1442. doi: 10.1124/dmd.119.088922. Epub 2019 Oct 3. Drug Metab Dispos. 2019. PMID: 31582395

6

In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation.

Liang X, Park Y, DeForest N, Hao J, Zhao X, Niu C, Wang K, Smith B, Lai Y. Liang X, et al. Drug Metab Dispos. 2020 Dec;48(12):1283-1292. doi: 10.1124/dmd.120.000163. Epub 2020 Oct 9. Drug Metab Dispos. 2020. PMID: 33037043

7

Comparison of Tissue Abundance of Non-Cytochrome P450 Drug-Metabolizing Enzymes by Quantitative Proteomics between Humans and Laboratory Animal Species.

Basit A, Fan PW, Khojasteh SC, Murray BP, Smith BJ, Heyward S, Prasad B. Basit A, et al. Among authors: smith bj. Drug Metab Dispos. 2022 Mar;50(3):197-203. doi: 10.1124/dmd.121.000774. Epub 2021 Dec 30. Drug Metab Dispos. 2022. PMID: 34969659

8

Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs.

Subash S, Singh DK, Ahire DS, Khojasteh SC, Murray BP, Zientek MA, Jones RS, Kulkarni P, Smith BJ, Heyward S, Cronin CN, Prasad B. Subash S, et al. Among authors: smith bj. Drug Metab Dispos. 2023 Oct;51(10):1362-1371. doi: 10.1124/dmd.123.001379. Epub 2023 Jul 10. Drug Metab Dispos. 2023. PMID: 37429730

9

Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine.

Zhang H, Wolford C, Basit A, Li AP, Fan PW, Murray BP, Takahashi RH, Khojasteh SC, Smith BJ, Thummel KE, Prasad B. Zhang H, et al. Among authors: smith bj. Drug Metab Dispos. 2020 Jul;48(7):528-536. doi: 10.1124/dmd.120.090738. Epub 2020 Apr 29. Drug Metab Dispos. 2020. PMID: 32350063

10

Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human.

Basit A, Neradugomma NK, Wolford C, Fan PW, Murray B, Takahashi RH, Khojasteh SC, Smith BJ, Heyward S, Totah RA, Kelly EJ, Prasad B. Basit A, et al. Among authors: smith bj. Mol Pharm. 2020 Nov 2;17(11):4114-4124. doi: 10.1021/acs.molpharmaceut.0c00559. Epub 2020 Oct 2. Mol Pharm. 2020. PMID: 32955894

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,339 results

Search Page

Filters