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355 results

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Page 1
LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Schelker RC, Fioravanti J, Mastrogiovanni F, Baldwin JG, Rana N, Li P, Chen P, Vadász T, Spolski R, Heuser-Loy C, Slavkovic-Lukic D, Noronha P, Damiano G, Raccosta L, Maggioni D, Pullugula S, Lin JX, Oh J, Grandinetti P, Lecce M, Hesse L, Kocks E, Martín-Santos A, Gebhard C, Telford WG, Ji Y, Restifo NP, Russo V, Rehli M, Herr W, Leonard WJ, Gattinoni L. Schelker RC, et al. Among authors: restifo np. Signal Transduct Target Ther. 2024 Aug 9;9(1):199. doi: 10.1038/s41392-024-01915-z. Signal Transduct Target Ther. 2024. PMID: 39117617 Free PMC article.
An engineered IL-2 partial agonist promotes CD8+ T cell stemness.
Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, Zhuang X, Mitra S, Lin JX, Gattinoni L, Powell JD, Restifo NP, Garcia KC, Leonard WJ. Mo F, et al. Among authors: restifo np. Nature. 2021 Sep;597(7877):544-548. doi: 10.1038/s41586-021-03861-0. Epub 2021 Sep 15. Nature. 2021. PMID: 34526724 Free PMC article.
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.
Zeng R, Spolski R, Finkelstein SE, Oh S, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA, Leonard WJ. Zeng R, et al. Among authors: restifo np. J Exp Med. 2005 Jan 3;201(1):139-48. doi: 10.1084/jem.20041057. J Exp Med. 2005. PMID: 15630141 Free PMC article.
Programming CD8+ T cells for effective immunotherapy.
Hinrichs CS, Gattinoni L, Restifo NP. Hinrichs CS, et al. Among authors: restifo np. Curr Opin Immunol. 2006 Jun;18(3):363-70. doi: 10.1016/j.coi.2006.03.009. Epub 2006 Apr 17. Curr Opin Immunol. 2006. PMID: 16616471 Free PMC article. Review.
CD8+ T-cell memory in tumor immunology and immunotherapy.
Klebanoff CA, Gattinoni L, Restifo NP. Klebanoff CA, et al. Among authors: restifo np. Immunol Rev. 2006 Jun;211:214-24. doi: 10.1111/j.0105-2896.2006.00391.x. Immunol Rev. 2006. PMID: 16824130 Free PMC article. Review.
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.
Hinrichs CS, Borman ZA, Cassard L, Gattinoni L, Spolski R, Yu Z, Sanchez-Perez L, Muranski P, Kern SJ, Logun C, Palmer DC, Ji Y, Reger RN, Leonard WJ, Danner RL, Rosenberg SA, Restifo NP. Hinrichs CS, et al. Among authors: restifo np. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17469-74. doi: 10.1073/pnas.0907448106. Epub 2009 Sep 24. Proc Natl Acad Sci U S A. 2009. PMID: 19805141 Free PMC article.
Paths to stemness: building the ultimate antitumour T cell.
Gattinoni L, Klebanoff CA, Restifo NP. Gattinoni L, et al. Among authors: restifo np. Nat Rev Cancer. 2012 Oct;12(10):671-84. doi: 10.1038/nrc3322. Epub 2012 Sep 21. Nat Rev Cancer. 2012. PMID: 22996603 Free PMC article. Review.
355 results