Raffaelli N - Search Results

1

Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high-affinity quinolinate binders with a potential role in NAD biosynthesis.

Sorci L, Minazzato G, Amici A, Mazzola F, Raffaelli N. Sorci L, et al. Among authors: raffaelli n. FEBS Open Bio. 2024 Oct;14(10):1718-1730. doi: 10.1002/2211-5463.13876. Epub 2024 Aug 8. FEBS Open Bio. 2024. PMID: 39118291 Free PMC article.

2

Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases.

Sorci L, Brunetti L, Cialabrini L, Mazzola F, Kazanov MD, D'Auria S, Ruggieri S, Raffaelli N. Sorci L, et al. Among authors: raffaelli n. FEBS Lett. 2014 Mar 18;588(6):1016-23. doi: 10.1016/j.febslet.2014.01.063. Epub 2014 Feb 11. FEBS Lett. 2014. PMID: 24530526 Free article.

3

Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD(+) biosynthetic machinery in mammalian cells.

Zamporlini F, Ruggieri S, Mazzola F, Amici A, Orsomando G, Raffaelli N. Zamporlini F, et al. Among authors: raffaelli n. FEBS J. 2014 Nov;281(22):5104-19. doi: 10.1111/febs.13050. Epub 2014 Oct 4. FEBS J. 2014. PMID: 25223558 Free article.

4

Functional Characterization of COG1713 (YqeK) as a Novel Diadenosine Tetraphosphate Hydrolase Family.

Minazzato G, Gasparrini M, Amici A, Cianci M, Mazzola F, Orsomando G, Sorci L, Raffaelli N. Minazzato G, et al. Among authors: raffaelli n. J Bacteriol. 2020 Apr 27;202(10):e00053-20. doi: 10.1128/JB.00053-20. Print 2020 Apr 27. J Bacteriol. 2020. PMID: 32152217 Free PMC article.

5

Enzymology of extracellular NAD metabolism.

Gasparrini M, Sorci L, Raffaelli N. Gasparrini M, et al. Among authors: raffaelli n. Cell Mol Life Sci. 2021 Apr;78(7):3317-3331. doi: 10.1007/s00018-020-03742-1. Epub 2021 Mar 23. Cell Mol Life Sci. 2021. PMID: 33755743 Free PMC article. Review.

6

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4.

Gasparrini M, Mazzola F, Cuccioloni M, Sorci L, Audrito V, Zamporlini F, Fortunato C, Amici A, Cianci M, Deaglio S, Angeletti M, Raffaelli N. Gasparrini M, et al. Among authors: raffaelli n. J Biol Chem. 2022 Mar;298(3):101669. doi: 10.1016/j.jbc.2022.101669. Epub 2022 Feb 2. J Biol Chem. 2022. PMID: 35120922 Free PMC article.

7

Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis.

Minazzato G, Gasparrini M, Heroux A, Sernova NV, Rodionov DA, Cianci M, Sorci L, Raffaelli N. Minazzato G, et al. Among authors: raffaelli n. J Struct Biol. 2022 Dec;214(4):107917. doi: 10.1016/j.jsb.2022.107917. Epub 2022 Nov 1. J Struct Biol. 2022. PMID: 36332744

8

Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis.

Raffaelli N, Finaurini L, Mazzola F, Pucci L, Sorci L, Amici A, Magni G. Raffaelli N, et al. Biochemistry. 2004 Jun 15;43(23):7610-7. doi: 10.1021/bi049650w. Biochemistry. 2004. PMID: 15182203

9

Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family.

Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N. Galeazzi L, et al. Among authors: raffaelli n. J Biol Chem. 2011 Nov 18;286(46):40365-75. doi: 10.1074/jbc.M111.275818. Epub 2011 Sep 27. J Biol Chem. 2011. PMID: 21953451 Free PMC article.

10

Genomics-guided analysis of NAD recycling yields functional elucidation of COG1058 as a new family of pyrophosphatases.

Cialabrini L, Ruggieri S, Kazanov MD, Sorci L, Mazzola F, Orsomando G, Osterman AL, Raffaelli N. Cialabrini L, et al. Among authors: raffaelli n. PLoS One. 2013 Jun 12;8(6):e65595. doi: 10.1371/journal.pone.0065595. Print 2013. PLoS One. 2013. PMID: 23776507 Free PMC article.

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