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Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.
Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: gardner a. Cancer Discov. 2024 Dec 2;14(12):2430-2449. doi: 10.1158/2159-8290.CD-23-0866. Cancer Discov. 2024. PMID: 39121480 Free PMC article.
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
Schade AE, Perurena N, Yang Y, Rodriguez CL, Krishnan A, Gardner A, Loi P, Xu Y, Nguyen VTM, Mastellone GM, Pilla NF, Watanabe M, Ota K, Davis RA, Mattioli K, Xiang D, Zoeller JJ, Lin JR, Morganti S, Garrido-Castro AC, Tolaney SM, Li Z, Barbie DA, Sorger PK, Helin K, Santagata S, Knott SRV, Cichowski K. Schade AE, et al. Among authors: gardner a. Nature. 2024 Nov;635(8039):755-763. doi: 10.1038/s41586-024-08031-6. Epub 2024 Oct 9. Nature. 2024. PMID: 39385030 Free PMC article.
Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.
Lester DK, Burton C, Gardner A, Innamarato P, Kodumudi K, Liu Q, Adhikari E, Ming Q, Williamson DB, Frederick DT, Sharova T, White MG, Markowitz J, Cao B, Nguyen J, Johnson J, Beatty M, Mockabee-Macias A, Mercurio M, Watson G, Chen PL, McCarthy S, MoranSegura C, Messina J, Thomas KL, Darville L, Izumi V, Koomen JM, Pilon-Thomas SA, Ruffell B, Luca VC, Haltiwanger RS, Wang X, Wargo JA, Boland GM, Lau EK. Lester DK, et al. Among authors: gardner a. Nat Cancer. 2023 Feb;4(2):222-239. doi: 10.1038/s43018-022-00506-7. Epub 2023 Jan 23. Nat Cancer. 2023. PMID: 36690875 Free PMC article.
Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity.
Hänggi K, Li J, Gangadharan A, Liu X, Celias DP, Osunmakinde O, Keske A, Davis J, Ahmad F, Giron A, Anadon CM, Gardner A, DeNardo DG, Shaw TI, Beg AA, Yu X, Ruffell B. Hänggi K, et al. Among authors: gardner a. Cancer Cell. 2024 Dec 9;42(12):2015-2031.e11. doi: 10.1016/j.ccell.2024.10.014. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577420
Dendritic Cells and Their Role in Immunotherapy.
Gardner A, de Mingo Pulido Á, Ruffell B. Gardner A, et al. Front Immunol. 2020 May 21;11:924. doi: 10.3389/fimmu.2020.00924. eCollection 2020. Front Immunol. 2020. PMID: 32508825 Free PMC article. Review.
Reducing interferon'ce in stem cells.
Gardner A, Ruffell B. Gardner A, et al. Nat Cell Biol. 2017 May 31;19(6):597-599. doi: 10.1038/ncb3544. Nat Cell Biol. 2017. PMID: 28561058
A tackler correctly adhering to the tackle instruction in a front-on, one-on-one torso tackle alters the peak inertial head kinematics of the ball carrier but not the tackler.
Edwards S, Gardner AJ, Tahu T, Quarrie KL, Fuller GW, Strangman G, Iverson GL, Tucker R. Edwards S, et al. Among authors: gardner aj. J Sci Med Sport. 2024 Nov 22:S1440-2440(24)00579-6. doi: 10.1016/j.jsams.2024.11.006. Online ahead of print. J Sci Med Sport. 2024. PMID: 39709290 Free article.
1,963 results